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Retreatment with erlotinib in NSCLC harboring EGFR mutation ? case report.

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F26475821%3A_____%2F12%3A%230000135" target="_blank" >RIV/26475821:_____/12:#0000135 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Retreatment with erlotinib in NSCLC harboring EGFR mutation ? case report.

  • Original language description

    One of the modern therapeutic modalities in pneumooncology is a treatment using tyrosine kinase inhibitors to block the activation of epidermal growth factor receptor (EGFR) cascade. Erlotinib (Tarceva?) is an EGFR tyrosine kinase inhibitor, in clinicalpractice commonly used for treatment of advanced non-small cell lung carcinoma (NSCLC). Activating mutations of EGFR gene, deletion at the 19th exon and point mutations to 21 exon (L858) are universally considered as a good predictor of response to EGFR-TKI treatment.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    FD - Oncology and haematology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/NS9718" target="_blank" >NS9718: New possibilities for application of molecular-diagnostic methods for early detection and proper therapy selection of progressing Non-Small Cell Lung Cancer based on detection and monitoring of hypermethylation of specific genes</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů