Metabolic disorders due to methanol poisoning

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F14%3AN0000001" target="_blank" >RIV/27661989:_____/14:N0000001 - isvavai.cz</a>

Alternative codes found

RIV/70883521:28610/14:43870533

Result on the web

<a href="https://biomed.papers.upol.cz/pdfs/bio/2014/04/22.pdf" target="_blank" >https://biomed.papers.upol.cz/pdfs/bio/2014/04/22.pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2013.074" target="_blank" >10.5507/bp.2013.074</a>

Result language

angličtina

Original language name

Metabolic disorders due to methanol poisoning

Original language description

Aim. The aim of this study is to compare markers of glomerular filtration rate (GFR), estimated GFR (eGFR), and metabolic parameters between admission and recovery in 13 patients of Tomas Bata hospital with methanol poisoning during methanol problems in the Czech Republic in 2012. The impact of methanol concentration and age on metabolic parameters were discovered at the time of admission to hospital. Materials and Methods. The serum osmolality, methanol, ethanol, creatinine, cystatin C, Troponin I, ALT, plasma pH and lactate were measured in these 13 patients. The eGFR from serum creatinine (creatnine eGFR) and from cystatin C (cystatin C eGFR) were also determined. Results. Increased serum osmolality and markers of metabolic acidosis are key indirect laboratory findings in patients with methanol poisoning. There were no significant changes in eGFR in our patients between admission and recovery. Increased serum troponin I concentration was confirmed as an indicator of myocardial necrosis in four patients. Two patients developed acute kidney injury (AKI) before admission. Conclusions. We found statistically significant differences in serum osmolality concentration, plasma pH and lactate between admission and recovery. We found no changes in eGFR between admission and recovery. One patient had vision problems due to damage to the occipital lobes. Methanol poisoning may cause increase in markers of cardiac damage.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30200 - Clinical medicine

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic

ISSN

1213-8118

e-ISSN

1804-7521

Volume of the periodical

158

Issue of the periodical within the volume

4

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

5

Pages from-to

635-639

UT code for WoS article

000347173200022

EID of the result in the Scopus database

2-s2.0-84916221761