Omission of adjuvant radiation therapy in elderly patients with low risk breast cancer undergoing breast-conserving surgery - two center experience

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F14%3AN0000014" target="_blank" >RIV/27661989:_____/14:N0000014 - isvavai.cz</a>

Alternative codes found

RIV/61989592:15110/13:33147991 RIV/00098892:_____/13:#0000585 RIV/70883521:28150/14:43871807 RIV/75010330:_____/14:00010639

Result on the web

<a href="https://biomed.papers.upol.cz/artkey/bio-201403-0021_omission_of_adjuvant_radiation_therapy_in_elderly_patients_with_low_risk_breast_cancer_undergoing_breast-conser.php" target="_blank" >https://biomed.papers.upol.cz/artkey/bio-201403-0021_omission_of_adjuvant_radiation_therapy_in_elderly_patients_with_low_risk_breast_cancer_undergoing_breast-conser.php</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5507/bp.2013.032" target="_blank" >10.5507/bp.2013.032</a>

Result language

angličtina

Original language name

Omission of adjuvant radiation therapy in elderly patients with low risk breast cancer undergoing breast-conserving surgery - two center experience

Original language description

Introduction. Breast cancer is, now often diagnosed in patients older than 70 years due to longer life expectancy. The usual treatment is mastectomy to obviate radiotherapy or breast-conserving surgery followed by radiotherapy. The aim of this study was to investigate the need for adjuvant radiotherapy in older patients and the consequences of omitting radiotherapy following conservative surgery. Methods. An extensive database search was made of patients who had been treated for breast cancer at the Department of Oncology, University Hospital Olomouc and the Atlas Hospital in Zlin (2004-2008). We identified 738 patients of whom 190 patients (25.7%) were older than 70 years of age. These were followed up for progression-free and overall survival. The cause of death was checked for breast cancer relapse. Results. In total only 9 patients undergoing breast saving surgery were ultimately identified. No patient had confirmed local recurrence during the follow up period: Two patients have died due to distant metastasis without local relapse and one patient has died for reasons other than breast cancer. Conclusion. Omitting radiotherapy after breast saving surgery provides an opportunity for women to undergo breast saving surgery and avoid 7 weeks of radiotherapy. This could significantly improve patient quality of life. In our of many years experience and from published randomized data, this procedure is safe for a select group of patients 70 years of age and older.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30204 - Oncology

Project

—

Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2014

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc Czech Republic

ISSN

1213-8118

e-ISSN

1804-7521

Volume of the periodical

158

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

4

Pages from-to

461-464

UT code for WoS article

000345398500021

EID of the result in the Scopus database

2-s2.0-84907623909