Nutrition status and comorbidities in patients with severe COPD
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F18%3AN0000021" target="_blank" >RIV/27661989:_____/18:N0000021 - isvavai.cz</a>
Result on the web
<a href="https://publications.ersnet.org/content/erj/52/suppl62/pa710" target="_blank" >https://publications.ersnet.org/content/erj/52/suppl62/pa710</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1183/13993003.congress-2018.PA710" target="_blank" >10.1183/13993003.congress-2018.PA710</a>
Alternative languages
Result language
angličtina
Original language name
Nutrition status and comorbidities in patients with severe COPD
Original language description
Aim: To assess comorbidities in patients with severe COPD according to nutrition status. Methods: We analysed baseline data of patients from The Czech National Registry of Severe COPD. Nutrition status (BMI, FFMI), comorbidities and their impact to mortality and other parameters were analysed. Results: A total of 343 patients were included into the analysis,253 men, mean age 66.6 years, mean FEV1 44.9%, average CAT 16.8. There were 10.2% patients with cachexia, 6.4% with underweight, 30.9% patients were obese. Total of 20.7% had muscle mass loss. There were significant differences of nutritional status according to COPD phenotypes, but not in GOLD groups. Patients with underweight had higher CAT (p=0.06), lower FEV1 (p=0.022), lower FEV1/VCmax (p<0.001) and lower TLCO (p<0.001) at baseline than obese patients, but there were no differences among the groups in declination of lung functions during 24 month follow up. Obesity was associated with higher frequency of diabetes mellitus (55%), heart failure (50%) and other cardiovascular disease. Overweight was associated with more comorbidities (about 30%), cachexia with osteoporosis (p=0.006) and depression. Other nutritional groups were associated with lower frequency of comorbidities. There were significant differences in mortality among nutritional groups. The highest mortality in 48 month follow up was in underweight patient and the lowest in overweight group (p<0.001). Conclusion: Poor nutrition is associated with certain COPD phenotypes, worse lung function, more symptoms and higher mortality. We found also differences in frequency of comorbidities in patients with severe COPD acoording to nutrition status that can affect its mortality and supports heterogenity COPD.
Czech name
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Czech description
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Classification
Type
J<sub>ost</sub> - Miscellaneous article in a specialist periodical
CEP classification
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OECD FORD branch
30203 - Respiratory systems
Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
European Respiratory Journal
ISSN
0903-1936
e-ISSN
1399-3003
Volume of the periodical
52
Issue of the periodical within the volume
Supplement 62
Country of publishing house
GB - UNITED KINGDOM
Number of pages
1
Pages from-to
PA710
UT code for WoS article
000455567107391
EID of the result in the Scopus database
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