1-year results after PCI with the COMBO stent in all -comers in Asia versus Europe: Geographical insights from the COMBO collaboration

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F20%3A10002772" target="_blank" >RIV/27661989:_____/20:10002772 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11130/20:10410895 RIV/65269705:_____/20:00072764 RIV/00064203:_____/20:10410895 RIV/00023884:_____/20:00008691

Result on the web

<a href="https://www.internationaljournalofcardiology.com/article/S0167-5273(19)35338-0/abstract" target="_blank" >https://www.internationaljournalofcardiology.com/article/S0167-5273(19)35338-0/abstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ijcard.2020.01.045" target="_blank" >10.1016/j.ijcard.2020.01.045</a>

Result language

angličtina

Original language name

1-year results after PCI with the COMBO stent in all -comers in Asia versus Europe: Geographical insights from the COMBO collaboration

Original language description

Background The COMBO drug-eluting stent combines sirolimus-elution from a biodegradable polymer with an anti-CD34+ antibody coating for early endothelialization. Objective We investigated for geographical differences in outcomes after percutaneous coronary intervention (PCI) with the COMBO stent among Asians and Europeans. Methods The COMBO Collaboration is a pooled patient-level analysis of the MASCOT and REMEDEE registries of all-comers undergoing attempted COMBO stent PCI. The primary outcome was 1-year target lesion failure (TLF), composite of cardiac death, target vessel myocardial infarction (TV-MI) and target lesion revascularization (TLR). Results This study included 604 Asians (17.9%) and 2775 Europeans (82.1%). Asians were younger and included fewer females, with a higher prevalence of diabetes mellitus but lower prevalence of other comorbidities than Europeans. Asians had a higher prevalence of ACC/AHA C type lesions and received longer stent lengths. More Asians than Europeans were discharged on clopidogrel (86.5% vs 62.8%) rather than potent P2Y12 inhibitors. One-year TLF occurred in 4.0% Asians and 4.1% of Europeans, p = 0.93. The incidence of cardiac death was higher in Asians (2.8% vs. 1.3%, p = 0.007) with similar rates of TV-MI (1.5% vs. 1.2%, p = 0.54) and definite stent thrombosis (0.3% vs. 0.5%, p = 0.84) and lower incidence of TLR than Europeans (1.0% vs. 2.5%, p = 0.025). After adjustment, differences for cardiac death and TLR were no longer significant.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30201 - Cardiac and Cardiovascular systems

Project

—

Continuities

N - Vyzkumna aktivita podporovana z neverejnych zdroju

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

International Journal of Cardiology

ISSN

0167-5273

e-ISSN

1874-1754

Volume of the periodical

307

Issue of the periodical within the volume

May

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

17-23

UT code for WoS article

000531648400005

EID of the result in the Scopus database

2-s2.0-85080039817