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Furosemide-associated hyponatremia in internal medicine patients: Analysis of epidemiological and biochemical profiles

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F27661989%3A_____%2F23%3A10003382" target="_blank" >RIV/27661989:_____/23:10003382 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.sciencedirect.com/science/article/abs/pii/S0953620523001450" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S0953620523001450</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1016/j.ejim.2023.04.033" target="_blank" >10.1016/j.ejim.2023.04.033</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Furosemide-associated hyponatremia in internal medicine patients: Analysis of epidemiological and biochemical profiles

  • Original language description

    This retrospective study evaluates epidemiological, biochemical and clinical characteristics of patients hospitalized with hypotonic hyponatremia who were treated with furosemide. A total of 504 patients were included, of whom 81 (16.1%) were receiving furosemide. These patients demonstrated higher in‑hospital mortality and markedly impaired renal function parameters, along with increased fractional excretion of sodium, potassium, chloride, and water. However, their biochemical profile did not correspond to the typical pattern of diuretic‑induced hyponatremia. A minority of patients treated with furosemide alone exhibited features of true hypovolemic hyponatremia, suggesting that furosemide may contribute to its development in selected cases. The study highlights the complexity of interpreting electrolyte disturbances in multimorbid patients frequently receiving combined diuretic therapy.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30218 - General and internal medicine

Result continuities

  • Project

  • Continuities

    N - Vyzkumna aktivita podporovana z neverejnych zdroju

Others

  • Publication year

    2023

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    European Journal of Internal Medicine

  • ISSN

    0953-6205

  • e-ISSN

    1879-0828

  • Volume of the periodical

    114

  • Issue of the periodical within the volume

    August

  • Country of publishing house

    NL - THE KINGDOM OF THE NETHERLANDS

  • Number of pages

    3

  • Pages from-to

    138-140

  • UT code for WoS article

    001052406300001

  • EID of the result in the Scopus database