Changes of Cardiac Biomarkers in Ultramarathon Runners
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13430%2F19%3A43894721" target="_blank" >RIV/44555601:13430/19:43894721 - isvavai.cz</a>
Result on the web
<a href="http://www.physactiv.eu/wp-content/uploads/2019/01/2019_11.pdf" target="_blank" >http://www.physactiv.eu/wp-content/uploads/2019/01/2019_11.pdf</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.16926/par.2019.07.11" target="_blank" >10.16926/par.2019.07.11</a>
Alternative languages
Result language
angličtina
Original language name
Changes of Cardiac Biomarkers in Ultramarathon Runners
Original language description
Introduction: The aim of this study is to examine and evaluate the effects of long-term stress on muscle and heart biomarkers after completing a 100 km ultramarathon. Material and Methods: Venous blood samples of nine runners (average age 38.8+-10.2 years), who successfully finished a 100 km ultramarathon at an elevation of 3130 m, were examined before the start, at the finish line immediately after the run, one day after the run and then after 5 and 10 days. Clinical, laboratory, and somatometric data were obtained from all measurements, and biomarkers: aspartate aminotransferase (AST), cortisol (COR), troponin T (cTnT), creatine kinase (CK) and C-reactive protein (CRP). Also, their training experience and ultramarathon experience was monitored. Discovered values were further analyzed with the use of t-test a ?2 (?2GREATER-THAN OR EQUAL TO0.1), and Spearman's rank correlation coefficient (r) at the significance level of p<0.05. Results: The average finish time of the runners was 13:55:40 (min: 12:12:35, max: 16:52:02). After finishing the ultramarathon, runners showed an average weight loss of 2.4 kg (p<0.05). The results show that hematological changes were caused by physiological stress and long-term physical load. The values of all monitored biomarkers showed a significant exceeding of the normal values immediately after the race in 8 competitors out of 9. The values of cTnT showed an increase of more than 50 % (pre-race: 8.2+-2.3, post-race: 34.22+-25.9 ng/l, max=98 ng/l). After 24 hours, however, this condition had returned to the normal values for all participants. The results show that the AST hepatic enzymes significantly correlated with the training experience (r=-0.41, p=0.043), the total number of kilometers run per year (r=-0.45, p=0.04) and the achieved finish time (r=0.67, p=0.001). At the same time, athletes who had the best finish time achieved lower CRP values (r=0.74, p=0.023) and cTnT values (r=0.49, p=0.040). The study found that the competitors who had the longest experience with ultramaraton had the lowest cTnT (r=0.44, p=0.050). Conclusion: Long-term physical stress is associated with metabolic and cardiovascular changes. Blood abnormalities found in our study suggest that due to long-lasting extreme stress, heart exhaustion may occur. However, these changes did not last long and after a few days they returned to the normal values for all runners.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30306 - Sport and fitness sciences
Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Physical Activity Review
ISSN
2300-5076
e-ISSN
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Volume of the periodical
7
Issue of the periodical within the volume
2019
Country of publishing house
PL - POLAND
Number of pages
7
Pages from-to
89-95
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85070957251