Lower A1C with Real-Time CGM than with Intermittently- Scanned CGM after One Year-The CORRIDA LIFE Study

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13430%2F22%3A43897553" target="_blank" >RIV/44555601:13430/22:43897553 - isvavai.cz</a>
Result on the web
<a href="https://diabetesjournals.org/diabetes/article/71/Supplement_1/70-LB/146202/70-LB-Lower-A1C-with-Real-Time-CGM-than-with" target="_blank" >https://diabetesjournals.org/diabetes/article/71/Supplement_1/70-LB/146202/70-LB-Lower-A1C-with-Real-Time-CGM-than-with</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.2337/db22-70-LB" target="_blank" >10.2337/db22-70-LB</a>

Result language
angličtina
Original language name
Lower A1C with Real-Time CGM than with Intermittently- Scanned CGM after One Year-The CORRIDA LIFE Study
Original language description
We investigated the efficacy of real-time continuous glucose monitoring (rtCGM) and intermittently scanned continuous glucose monitoring (isCGM) on change in A1C. CORRIDA LIFE was a 12 month, real-world, non-randomized trial that assessed the impact of rtCGM (Dexcom G5 or G6) vs. isCGM (FreeStyle Libre 14-Day, Abbott) on A1C and other CGM metrics in adults with T1D. Patients on MDI therapy or CSII with no automatic functions were included. One hundred ninety-one adults with T1D (mean age 40?13 years, A1C 8.1?3.4% [65?14 mmol/mol]) participated in this study; 81 patients initiated rtCGM and 110 initiated isCGM. After 12-months, A1C was significantly lower with rtCGM vs. isCGM (7.1?3.1% [54.1?10.1 mmol/mol] vs. 7.7?3.3% [61.2?12.2 mmol/mol]) , p=0.0001. (Figure 1) The percentage of time in hypoglycemia (<70 mg/dL [<3.9 mmol/L]) was lower among rtCGM vs. isCGM participants (4.3?2.8% vs. 6.4?5.3%) , p=0.003) . Patients with rtCGM spent less time in clinically significant hypoglycemia (<54 mg/dL [<3.0 mmol/L]) (0.9?1.0% vs. 2.3?2.5%, p<0.0001) and more time in target range (70-180 mg/dL [3.9-10 mmol/L]) than isCGM users (67.5?14.8% vs. 57.8?17.0%) , p=0.0002. Use of rtCGM was superior to isCGM in reducing A1C and hypoglycemia and improving other glycemic outcomes.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
30502 - Other medical science

Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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