Simulation of the effect of ethanol on DNA damage by ionizing radiation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13440%2F24%3A43898696" target="_blank" >RIV/44555601:13440/24:43898696 - isvavai.cz</a>
Result on the web
<a href="https://www.tandfonline.com/doi/full/10.1080/10420150.2024.2424755" target="_blank" >https://www.tandfonline.com/doi/full/10.1080/10420150.2024.2424755</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/10420150.2024.2424755" target="_blank" >10.1080/10420150.2024.2424755</a>
Alternative languages
Result language
angličtina
Original language name
Simulation of the effect of ethanol on DNA damage by ionizing radiation
Original language description
The presence of ethanol in the water solution during irradiation by ionizing radiation decreases the number of OH and H radicals. Since the living cell is mainly composed of water, this causes less damage to the DNA molecule irradiated by low-LET ionizing radiation where an indirect effect prevails. Ethanol thus acts as a radioprotective substance, scavenging radicals H and OH. This fact can be used in various practical applications in which living cells are irradiated by ionizing radiation to protect them. We used hybrid Petri nets to simulate all dynamic processes, including chemical reactions and the simultaneous diffusion of radical clusters. The mathematical simulatingmodel enables us to simulate the damage to the DNA moleculeby the radical cluster arising at various distances from this molecule.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Radiation effects and defects in solids
ISSN
1042-0150
e-ISSN
1029-4953
Volume of the periodical
2024
Issue of the periodical within the volume
"necislovano"
Country of publishing house
GB - UNITED KINGDOM
Number of pages
14
Pages from-to
"nestrankovano"
UT code for WoS article
001365793300001
EID of the result in the Scopus database
2-s2.0-85210566702