In Essential Hypertension, a Change in the Renal Resistive Index is Associated With a Change in the Ratio of 24-hour Diastolic to Systolic Blood Pressure

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13450%2F22%3A43897079" target="_blank" >RIV/44555601:13450/22:43897079 - isvavai.cz</a>

Result on the web

<a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470095/" target="_blank" >https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9470095/</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.33549/physiolres.934860" target="_blank" >10.33549/physiolres.934860</a>

Result language

angličtina

Original language name

In Essential Hypertension, a Change in the Renal Resistive Index is Associated With a Change in the Ratio of 24-hour Diastolic to Systolic Blood Pressure

Original language description

An increase in the renal resistive index (RRI) in patients with essential hypertension (EH) predicts deterioration in renal function. In patients with EH, changes in hemodynamic parameters significantly affect the RRI. This study aimed to define changes in Ambulatory Blood Pressure Monitoring (ABPM) parameters that are significantly associated with a change in RRI in patients with EH. We evaluated ABPM and the RRI in 96 patients with EH without organ extrarenal changes at baseline and after two years of follow-up. The relationships between changes in ABPM parameters and the RRI over the period were evaluated. After two years of follow-up, the increase in RRI was consequential. Simultaneously, 24-h systolic blood pressure increased significantly and 24-h diastolic blood pressure decreased. In the whole group and in the group with calculated cystatin C clearance (eGFRcyst) &gt;= 90 ml/min/1.73 m(2), the change in RRI significantly negatively correlated with the change in the ratio of 24-h diastolic to systolic blood pressure (D/S ratio), but also with the change in 24-h pulse blood pressure. However, in patients with eGFRcyst&lt;90 ml/min/1.73 m(2), only the change in the 24-h D/S ratio significantly correlated with the change in RRI. Based on the backward stepwise regression analysis, the change in RRI was significantly dependent only on the change in 24-h D/S ratio and not on the change in 24-h pulse pressure. A change in the ratio of diastolic to systolic pressure better reflects a change in RRI than a change in pulse pressure.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30218 - General and internal medicine

Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Physiological Research

ISSN

1802-9973

e-ISSN

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Volume of the periodical

71

Issue of the periodical within the volume

3

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

341-348

UT code for WoS article

000834967500002

EID of the result in the Scopus database

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