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Reactive synovitis of the knee joint after COVID-19 vaccination: The first ultrastructural analysis of synovial fluid

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13450%2F22%3A43897301" target="_blank" >RIV/44555601:13450/22:43897301 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11130/22:10445687 RIV/00216208:11150/22:10445687

  • Result on the web

    <a href="https://onlinelibrary.wiley.com/doi/10.1111/1756-185X.14411" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1111/1756-185X.14411</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1111/1756-185X.14411" target="_blank" >10.1111/1756-185X.14411</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Reactive synovitis of the knee joint after COVID-19 vaccination: The first ultrastructural analysis of synovial fluid

  • Original language description

    Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the resulting coronavirus 2019 disease (COVID-19) have spread all around the world since 2019 and have affected millions of people. The development of COVID-19 vaccines helped to decelerate the spread of the virus. However, as in the case of vaccines against other infectious diseases, adverse events can also present with COVID-19 vaccines. Case Presentation We report here a rare case of a 53-year-old man with knee-joint synovitis, after the first dose of messenger RNA vaccine, with no fever and a negative COVID-19 reverse transcription polymerase chain reaction test. During a clinical examination the suspicion of pyogenic arthritis was excluded by blood tests and by a complex joint effusion examination, including a microbiological and cytological-energy analysis of the synovial fluid. The treatment received by our patient consisted of 3 doses of dexamethasone administered intravenously over a period of 3 days. All the symptoms improved after this therapy, and in the 3-week follow-up period we recorded full recovery with no consequences. Conclusion Case reports on patients undergoing COVID-19 vaccination should be examined in order to detect rare and long-term side-effects. This is the first report to present the outcomes of an ultrastructural analysis of post-vaccination synovitis.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    30226 - Rheumatology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2022

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    International Journal of Rheumatic Diseases

  • ISSN

    1756-1841

  • e-ISSN

    1756-185X

  • Volume of the periodical

    25

  • Issue of the periodical within the volume

    11

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    4

  • Pages from-to

    1324-1327

  • UT code for WoS article

    000836126700001

  • EID of the result in the Scopus database