Shock Index for Early Detection of Low Plasma Fibrinogen in Trauma: A Prospective Observational Cohort Pilot Study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F44555601%3A13450%2F23%3A43898505" target="_blank" >RIV/44555601:13450/23:43898505 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11140/23:10458386 RIV/00216208:11150/23:10458386 RIV/00669806:_____/23:10458386

Result on the web

<a href="https://www.mdpi.com/2077-0383/12/4/1707" target="_blank" >https://www.mdpi.com/2077-0383/12/4/1707</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/jcm12041707" target="_blank" >10.3390/jcm12041707</a>

Result language

angličtina

Original language name

Shock Index for Early Detection of Low Plasma Fibrinogen in Trauma: A Prospective Observational Cohort Pilot Study

Original language description

first_pagesettingsOrder Article ReprintsOpen AccessArticleShock Index for Early Detection of Low Plasma Fibrinogen in Trauma: A Prospective Observational Cohort Pilot Studyby Josef Škola 1,2,*ORCID,Marcela Bílská 1,2,?,Michala Horáková 3,4,?,Václav Tégl 3,4,Jan Beneš 3,4ORCID,Roman Škulec 1,2 andVladimír Černý 1,21Department of Anaesthesiology, Perioperative Medicine and Intensive Care, J. E. Purkinje University, Masaryk Hospital in Usti nad Labem, Socialni Pece 3316/12A, 401 13 Usti nad Labem, Czech Republic2Faculty of Medicine in Hradec Kralove, Charles University, Šimkova 870, 500 03 Hradec Kralove, Czech Republic3Department of Anaesthesiology, Resuscitation and Intensive Care, Faculty of Medicine in Pilsen, Charles University, Alej Svobody 80, 304 60 Plzen-Lochotin, Czech Republic4Department of Anaesthesiology, Resuscitation and Intensive Care, University Hospital in Pilsen, Alej Svobody 80, 304 60 Plzen-Lochotin, Czech Republic*Author to whom correspondence should be addressed.?These authors contributed equally to this work.J. Clin. Med. 2023, 12(4), 1707; https://doi.org/10.3390/jcm12041707Submission received: 6 January 2023 / Revised: 10 February 2023 / Accepted: 17 February 2023 / Published: 20 February 2023(This article belongs to the Section Emergency Medicine)Downloadkeyboard_arrow_down Browse Figures Review Reports Versions NotesAbstractShock index (a ratio between heart rate and systolic blood pressure) predicts transfusion requirements and the need for haemostatic resuscitation in severe trauma patients. In the present study, we aimed to determine whether prehospital and on-admission shock index values can be used to predict low plasma fibrinogen in trauma patients. Between January 2016 and February 2017, trauma patients admitted from the helicopter emergency medical service into two large trauma centres in the Czech Republic were prospectively assessed for demographic, laboratory and trauma-associated variables and shock index at scene, during transport and at admission to the emergency department. Hypofibrinogenemia defined as fibrinogen plasma level of 1.5 g?L?l was deemed as a cut-off for further analysis. Three hundred and twenty-two patients were screened for eligibility. Of these, 264 (83%) were included for further analysis. The hypofibrinogenemia was predicted by the worst prehospital shock index with the area under the receiver operating characteristics curve (AUROC) of 0.79 (95% CI 0.64?0.91) and by the admission shock index with AUROC of 0.79 (95% CI 0.66?0.91). For predicting hypofibrinogenemia, the prehospital shock index ? 1 has 0.5 sensitivity (95% CI 0.19?0.81), 0.88 specificity (95% CI 0.83?0.92) and a negative predictive value of 0.98 (0.96?0.99). The shock index may help to identify trauma patients at risk of hypofibrinogenemia early in the prehospital course.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30221 - Critical care medicine and Emergency medicine

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2023

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Clinical Medicine

ISSN

2077-0383

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

4

Country of publishing house

CH - SWITZERLAND

Number of pages

10

Pages from-to

1-10

UT code for WoS article

000945091400001

EID of the result in the Scopus database

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