All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Left–right differences in the proximal femur’s strength of post-menopausal women: a multicentric finite element study

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F15%3A00002601" target="_blank" >RIV/46747885:24210/15:00002601 - isvavai.cz</a>

  • Result on the web

    <a href="http://link.springer.com/article/10.1007/s00198-015-3404-7" target="_blank" >http://link.springer.com/article/10.1007/s00198-015-3404-7</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00198-015-3404-7" target="_blank" >10.1007/s00198-015-3404-7</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Left–right differences in the proximal femur’s strength of post-menopausal women: a multicentric finite element study

  • Original language description

    © 2015, International Osteoporosis Foundation and National Osteoporosis Foundation. Summary: The strength of both femurs was estimated in 198 post-menopausal women through subject-specific finite element models. Important random differences between contralateral femurs were found in a significant number of subjects, pointing to the usefulness of further studies to understand if strength-based classification of patients at risk of fracture can be affected by laterality issues. Introduction: Significant, although small, differences exist in mineral density and anatomy of contralateral proximal femurs. These differences, and their combined effect, may result in a side difference in femurs’ strength. However, this has never been tested on a large sample of a homogenous population. Methods: The strength of both femurs was estimated in 198 post-menopausal women through CT-derived finite element models, built using a validated procedure, in sideways fall conditions. The impact of the resulting asymmetry on the classification of subjects at risk of fracture was analysed. Results: The small difference observed between sides (the right femur on average 4 % stronger than the left) was statistically significant but mechanically negligible. In contrast, higher random differences (absolute difference between sides with respect to mean value) were found: on average close to 15 % (compared to 9.2 % for areal bone mineral density (aBMD) alone), with high scatter among the subjects. When using a threshold-based classification, the right and left femurs were discordant up to over 20 % of cases (K always lower than 0.60) but the left femur was concordant (mean K = 0.84) with the minimum strength between right and left. Conclusion: Considering both femurs may be important when trying to classify subjects at risk of failure with strength estimates. Future studies including fracture assessment would be necessary to quantify the real impact.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    20301 - Mechanical engineering

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Osteoporosis International

  • ISSN

    0937-941X

  • e-ISSN

  • Volume of the periodical

    27

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    10

  • Pages from-to

    1519-1528

  • UT code for WoS article

    000372304400016

  • EID of the result in the Scopus database

    2-s2.0-84961056843