The Influence of Diamond Nanoparticles on Fibroblast Cell Line L929, Cytotoxicity and Bacteriostaticity of Selected Pathogens

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F22%3A00009394" target="_blank" >RIV/46747885:24210/22:00009394 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/2079-6412/12/2/280/pdf" target="_blank" >https://www.mdpi.com/2079-6412/12/2/280/pdf</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/coatings12101373" target="_blank" >10.3390/coatings12101373</a>

Result language

angličtina

Original language name

The Influence of Diamond Nanoparticles on Fibroblast Cell Line L929, Cytotoxicity and Bacteriostaticity of Selected Pathogens

Original language description

The main problem with using modified allotrophic forms of carbon with nanodiamond particles in the production of food packaging is establishing the boundary between safety, as it affects the human body, and the adequate and effective action of the substances. One vital area of concern is the transmission of pathogens in food into the body. The aim of this study was to evaluate the cytotoxicity and bacteriostatic biological activity of two different modifications of diamond nanoparticles: pure detonation nanodiamond particles (DND) obtained by Danienko and plasmachemically modified detonation nanodiamond particles obtained by the microwave plasma activated chemical vapor deposition method in a rotary chamber (MDP1) An indirect method was used to evaluate the cytotoxicity effect in accordance with ISO 10993–5. The viability of the L929 fibroblast cell line used as a control was 98.5%, for DND 95.14%, and the lowest level of viability for MDP1 was 88.63%. Escherichia coli and Staphylococcus aureus bacteria were used in bacteriostatic tests and the degree of cytotoxicity of the tested materials was classified as low. The in vitro cytotoxicity results indicate no toxic effect on L929 cells nor any effect on any of the samples tested against the bacterial strains us.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

20506 - Coating and films

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Coatings

ISSN

2079-6412

e-ISSN

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Volume of the periodical

12

Issue of the periodical within the volume

280

Country of publishing house

CH - SWITZERLAND

Number of pages

12

Pages from-to

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UT code for WoS article

000763375000001

EID of the result in the Scopus database

2-s2.0-85125146257