Alternating Current Electrospinning: A Novel and Efficient Fabrication Method for Curcumin-Loaded Polylactic Acid Nanofibers Compared to Direct Current Electrospinning
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F25%3A00013623" target="_blank" >RIV/46747885:24210/25:00013623 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24410/25:00013623 RIV/46747885:24510/25:00013623
Result on the web
<a href="https://doi.org/10.1002/app.57585" target="_blank" >https://doi.org/10.1002/app.57585</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/app.57585" target="_blank" >10.1002/app.57585</a>
Alternative languages
Result language
angličtina
Original language name
Alternating Current Electrospinning: A Novel and Efficient Fabrication Method for Curcumin-Loaded Polylactic Acid Nanofibers Compared to Direct Current Electrospinning
Original language description
This study compares nanofibrous materials produced via needleless alternating current (AC) (novel technology) and needleless direct current (DC) electrospinning. AC electrospinning was carried out using unique laboratory equipment, while DC electrospinning was performed on the Nanospider. Identical input data were employed to ensure consistency in the evaluation, including the use of the same polymer, solvent system, model substance, and its concentrations during AC and DC electrospinning. The polylactic acid (PLA) nanofibers are loaded with curcumin (CUR) at concentrations of 10% wt., 25% wt., and 50% wt. relative to the PLA content, while the control samples consist of pristine PLA fibers. This study demonstrates that the efficiency of needleless AC electrospinning is almost twice as high, reaching 11.2 ± 0.6 g/h, compared to needleless DC electrospinning, which has an efficiency of 5.2 ± 1.1 g/h. Nanofibrous materials produced via AC electrospinning exhibit larger fiber diameters with greater standard deviations, higher hydrophilicity after ethylene oxide sterilization (contact angle ranging from 23° to 58°), and higher pore sizes. In contrast, nanofibrous materials produced via DC electrospinning are characterized by smaller and more homogeneous fiber diameters and smaller pore sizes. The DC electrospinning technology enables a slightly higher drug loading efficiency.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10404 - Polymer science
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Applied Polymer Science>
ISSN
0021-8995
e-ISSN
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Volume of the periodical
142
Issue of the periodical within the volume
41
Country of publishing house
US - UNITED STATES
Number of pages
17
Pages from-to
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UT code for WoS article
001522757500001
EID of the result in the Scopus database
2-s2.0-105009829311