Cost-efficient and rapid fabrication of PCB-based microfluidic molds using a CNC approach without cleanroom requirements

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24210%2F25%3A00013778" target="_blank" >RIV/46747885:24210/25:00013778 - isvavai.cz</a>

Alternative codes found

RIV/46747885:24620/25:00013778

Result on the web

<a href="https://doi.org/10.1016/j.microc.2025.115015" target="_blank" >https://doi.org/10.1016/j.microc.2025.115015</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.microc.2025.115015" target="_blank" >10.1016/j.microc.2025.115015</a>

Result language

angličtina

Original language name

Cost-efficient and rapid fabrication of PCB-based microfluidic molds using a CNC approach without cleanroom requirements

Original language description

A widely utilized approach for manufacturing biomedical microfluidic devices involves the application of soft-lithography technology. Nevertheless, the development of molds for fabricating microfluidic devices, such as SU-8 molds, usually involves a cleanroom environment, which can be rather expensive. Consequently, numerous initiatives have been undertaken to develop inexpensive substitutes for microstructure production, thereby eliminating the need for cleanroom facilities. Non-lithographic low-cost approaches have gained interest from the industrial and research communities for their potential to produce microfluidic structures on a wide scale. These techniques are simple, quick, and cost-effective. In this study, we proposed an efficient method for the mass production of microfluidic devices for determining liquid concentration. Computer numerical control (CNC) micro-milling was the main process and a cost-effective alternative for fabricating microfluidic devices. The study also presents a strategy to remove the burr of the master mold to achieve better quality compared to the standard cleaning and burr removal process. To examine the proposed CNC master mold, printed circuit board (PCB)-based microfluidic devices were fabricated and evaluated. The capability of the device was tested by measuring the capacitance of the liquid concentration. Our findings signify progress towards a cost-effective aluminum master mold with microstructure, intended for the mass production of microfluidic devices. The device potentially valuable basic component for monitoring fluid mixing in microfluidic systems.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10406 - Analytical chemistry

Project

<a href="/en/project/EF16_025%2F0007293" target="_blank" >EF16_025/0007293: Modular platform for autonomous chassis of specialized electric vehicles for freight and equipment transportation</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Microchemical Journal>

ISSN

0026-265X

e-ISSN

—

Volume of the periodical

217

Issue of the periodical within the volume

OCT

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

8

Pages from-to

—

UT code for WoS article

001595312600015

EID of the result in the Scopus database

2-s2.0-105014411153