The GaPO4 Biosensor´s Affinity and its Electronic Evaluation

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24220%2F13%3A%230002465" target="_blank" >RIV/46747885:24220/13:#0002465 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
The GaPO4 Biosensor´s Affinity and its Electronic Evaluation
Original language description
This paper deals with the formation of the ASC immunocomplex at the surface of the Y-cut GaPO4 resonator vibrating in thickness-shear mode, of the orientation YXl (-16.4°). The following tasks were considered: activation by the cystamine, glutaraldehyde,and albumine as bioactive buffer, ASC antibody solution with phosphate buffer, and regeneration of the biosensor. The binding curves of series resonance frequency fs vs. time t were measured and discussed. Newly developed digital processing techniques are used to precise the measurement and to evaluate the frequency changes. The Field Programmable Gate Array circuits (FPGA) open the field of digital signal processing. Our solution uses the digital down converter (DDC) for evaluation of frequency changes. This solution reduces the cost of the biosensor unit and brings the concept of ?lab on chip?. The resolution of the GaPO4 biosensor remains unchanged, and biosensor sensitivity is increased.
Czech name
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Czech description
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Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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