Sulfate radical-mediated degradation of vancomycin: Kinetics, mechanism, and toxicity evaluation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24220%2F25%3A00013629" target="_blank" >RIV/46747885:24220/25:00013629 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24620/25:00013629
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S1383586625035324" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1383586625035324</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.seppur.2025.134935" target="_blank" >10.1016/j.seppur.2025.134935</a>
Alternative languages
Result language
angličtina
Original language name
Sulfate radical-mediated degradation of vancomycin: Kinetics, mechanism, and toxicity evaluation
Original language description
Sulfate radical-based process (SRP) is a class of remediation technologies that may be more effective under certain circumstances than conventional oxidation methods. This study investigated a thermally (30–60 °C) activated persulfate to degrade vancomycin (VAN), an organic micropollutant in water. The bimolecular rate constant between sulfate radical and VAN was determined by competition kinetics to be 3.4 × 108 M−1 s−1. The acidic and alkaline pH and common natural water constituents [HCO3–, Cl– and humic acid (HA)] influence the VAN oxidation by the sulfate radical (however, VAN at a concentration of 6.9 µM was always completely degraded in less than one hour). The scavenging test showed that the sulfate radicals (SO4) were responsible for VAN degradation; however, the observed increase in degradation in the presence of HCO3− suggests the involvement of an additional radical species, CO3. An oxidation by-product (acetylated VAN also without CH3N fraction) was predicted by the quantum chemical calculations and verified by HPLC-qTOF-HRMS analysis. Furthermore, it was proven by Algaltoxkit F toxicity test that the by-product was much less toxic for Selenastrum capricornutum microalgae than VAN. It may be concluded that the reaction of sulfate radicals with VAN is fast (3.4 × 108 M−1 s−1), and due to the high selectivity of sulfate radicals to electron-rich moieties, it can be efficiently applied for VAN removal in various environmental matrices.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20401 - Chemical engineering (plants, products)
Result continuities
Project
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Continuities
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Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Separation and Purification Technology>
ISSN
1383-5866
e-ISSN
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Volume of the periodical
379
Issue of the periodical within the volume
2
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
11
Pages from-to
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UT code for WoS article
001568018900001
EID of the result in the Scopus database
2-s2.0-105015143776