Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblast
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F12%3A%230001069" target="_blank" >RIV/46747885:24410/12:#0001069 - isvavai.cz</a>
Result on the web
<a href="http://www.hindawi.com/journals/jbb/2012/428503/" target="_blank" >http://www.hindawi.com/journals/jbb/2012/428503/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1155/2012/428503" target="_blank" >10.1155/2012/428503</a>
Alternative languages
Result language
angličtina
Original language name
Thin-Layer Hydroxyapatite Deposition on a Nanofiber Surface Stimulates Mesenchymal Stem Cell Proliferation and Their Differentiation into Osteoblast
Original language description
Pulsed laser deposition was proved as a suitable method for hydroxyapatite (HA) coating of coaxial poly-?-caprolactone/polyvinylalcohol (PCL/PVA) nanofibers. The fibrous morphology of PCL/PVA nanofibers was preserved, if the nanofiber scaffold was coatedwith thin layers of HA (200?nm and 400?nm). Increasing thickness of HA, however, resulted in a gradual loss of fibrous character. In addition, biomechanical properties were improved after HA deposition on PCL/PVA nanofibers as the value of Young's moduli of elasticity significantly increased. Clearly, thin-layer hydroxyapatite deposition on a nanofiber surface stimulated mesenchymal stem cell viability and their differentiation into osteoblasts. The optimal depth of HA was 800?nm.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
EI - Biotechnology and bionics
OECD FORD branch
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Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Biomedicine and Biotechnology
ISSN
1110-7243
e-ISSN
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Volume of the periodical
428503
Issue of the periodical within the volume
2012
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
1-10
UT code for WoS article
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EID of the result in the Scopus database
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