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Nanofiber Tubes as Vascular Grafts

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F12%3A%230001150" target="_blank" >RIV/46747885:24410/12:#0001150 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Nanofiber Tubes as Vascular Grafts

  • Original language description

    Tubes as vascular grafts made of polymeric nanofibers are very promising technology in the field of tissue engineering. A tube produced by an electrospinning technology consists of 2 layers. The choice of polymers plays an important role for electrospinning and can improve many different requests. The first layer was made from polycaprolactone (PCL) to ensure mechanical properties and the second layer was electrospun from pure chitosan (CS) which could improve the cytocompatibility of the tube for vascular tissue engineering. Vacular scaffolds fabricated by electrospinning of synthetic and natural polymers have been designed to provide adequate mechanical support as well as favorable adhesion substrate for vascular cells. PCL is frequently used vascular scaffold biomaterial because of its mechanical strength and ease of fabrication but also lacks blood and cellular biocompatibility because of its hydrophobicity. Natural polymers improve the cytocompatibility of the scaffold. The morpoh

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    FJ - Surgery including transplantology

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2012

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů