Nanofiber Tubes as Vascular Grafts
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F12%3A%230001150" target="_blank" >RIV/46747885:24410/12:#0001150 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Nanofiber Tubes as Vascular Grafts
Original language description
Tubes as vascular grafts made of polymeric nanofibers are very promising technology in the field of tissue engineering. A tube produced by an electrospinning technology consists of 2 layers. The choice of polymers plays an important role for electrospinning and can improve many different requests. The first layer was made from polycaprolactone (PCL) to ensure mechanical properties and the second layer was electrospun from pure chitosan (CS) which could improve the cytocompatibility of the tube for vascular tissue engineering. Vacular scaffolds fabricated by electrospinning of synthetic and natural polymers have been designed to provide adequate mechanical support as well as favorable adhesion substrate for vascular cells. PCL is frequently used vascular scaffold biomaterial because of its mechanical strength and ease of fabrication but also lacks blood and cellular biocompatibility because of its hydrophobicity. Natural polymers improve the cytocompatibility of the scaffold. The morpoh
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Result continuities
Project
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Continuities
S - Specificky vyzkum na vysokych skolach
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů