Suitability of Lyophilized Polymers based on CMC for Cell Proliferation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F15%3A00002536" target="_blank" >RIV/46747885:24410/15:00002536 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24620/15:00002536
Result on the web
<a href="http://www.nanocon.eu/cz/" target="_blank" >http://www.nanocon.eu/cz/</a>
DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Suitability of Lyophilized Polymers based on CMC for Cell Proliferation
Original language description
The aim of the study was to develop a material suitable for wound dressing which would be also suitable for cell growth and cell proliferation. Such matrix should have the structure of interconnected pores and a high porosity to ensure the adequate penetration of the cells and the supply of nutrients to the cells during their formation, diffusion of waste products out of the matrix and exclusion the products of matrix degradation. The study is focused on optimization the method of preparation of 3D porous structures and subsequent testing of cytotoxicity of thus prepared structures. The cytotoxicity of the structers was tested on human skin fibroblast cells. The cytotoxicity was tested by measuring the cell viability and using XTT assay. Another performed test was the test of biocidity/biodegradability. XTT assay results demonstrated that the lyophilized sample of carboxymethylcellulose is suitable for cell proliferation. Better cell proliferation is also caused by the increase of porosity made by lyophilization.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
CD - Macromolecular chemistry
OECD FORD branch
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Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
NANOCON 2015: 7TH INTERNATIONAL CONFERENCE ON NANOMATERIALS - RESEARCH & APPLICATION
ISBN
978-80-87294-63-5
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
565-570
Publisher name
Tanger Ltd. Ostrava
Place of publication
Ostrava
Event location
Brno
Event date
Jan 1, 2015
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000374708800099