Fabrication of Silk Fibroin Nanofibres by Needleless Electrospinning

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F16%3A00000760" target="_blank" >RIV/46747885:24410/16:00000760 - isvavai.cz</a>

Alternative codes found

RIV/46747885:24620/16:00000760

Result on the web

<a href="http://www.intechopen.com/books/electrospinning-material-techniques-and-biomedical-applications/fabrication-of-silk-fibroin-nanofibres-by-needleless-electrospinning" target="_blank" >http://www.intechopen.com/books/electrospinning-material-techniques-and-biomedical-applications/fabrication-of-silk-fibroin-nanofibres-by-needleless-electrospinning</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.5772/65835" target="_blank" >10.5772/65835</a>

Result language

angličtina

Original language name

Fabrication of Silk Fibroin Nanofibres by Needleless Electrospinning

Original language description

Silk fibroin nanofibres were fabricated using a needleless electrospinning technique. The procedure focused on a new method for the preparation of a spinning solution from silk fibroin. The role of the concentration of silk fibroin solution, applied voltage and spinning distance were investigated as a function of the morphology of the obtained fibres and the spinning performance of the electrospinning process. The biocompatibility of the obtained fibre sheets was evaluated using an in vitro testing method with MG-63 osteoblasts. The solvent system consisted of formic acid and calcium chloride that can dissolve silk fibroin at room temperature, and a rate of 0.25 g of calcium chloride per 1 g of silk fibroin was required to obtain a completely dissolved silk fibroin solution. The diameters of the silk electrospun fibres obtained from the formic acid–calcium chloride solvent system ranged from 100 to 2400 nm, depending on the spinning parameters. Furthermore, increasing the concentration of the silk fibroin solution and the applied voltage improved spinning ability and spinning performance in needleless electrospinning. In addition, in vitro tests with living cells showed that the obtained electrospun fibre sheets were highly biocompatible with MG-63 osteoblasts.

Czech name

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Czech description

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Type

C - Chapter in a specialist book

CEP classification

JJ - Other materials

OECD FORD branch

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Project

<a href="/en/project/LO1201" target="_blank" >LO1201: DEVELOPMENT OF THE INSTITUTE FOR NANOMATERIALS, ADVANCED TECHNOLOGIES AND INNOVATION</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Book/collection name

Electrospinning - Material, Techniques, and Biomedical Application

ISBN

978-953-51-2821-2

Number of pages of the result

19

Pages from-to

95-113

Number of pages of the book

155

Publisher name

Intech

Place of publication

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UT code for WoS chapter

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