Protein adsorption on biodegradable mikro/nanofibres materials for tissue engineering
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24410%2F24%3A00011662" target="_blank" >RIV/46747885:24410/24:00011662 - isvavai.cz</a>
Alternative codes found
RIV/46747885:24510/24:00011662 RIV/46747885:24620/24:00011662
Result on the web
<a href="https://doi.org/10.37904/nanocon.2023.4795" target="_blank" >https://doi.org/10.37904/nanocon.2023.4795</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.37904/nanocon.2023.4795" target="_blank" >10.37904/nanocon.2023.4795</a>
Alternative languages
Result language
angličtina
Original language name
Protein adsorption on biodegradable mikro/nanofibres materials for tissue engineering
Original language description
Due to their specific properties, nanofibrous materials are increasingly used in regenerative medicine and tissue engineering. Nanofibrous materials can be used as tissue scaffolds for injured (damaged) tissue. The main factor for tissue scaffolds is their biocompatibility. One of the main factors influencing the organism‘s physiological response is the interaction of the material with proteins. Proteins adsorbed on the material‘s surface give the tissue scaffolds a „biological identity”. Cells in the organism subsequently interact with proteins adsorbed on the material‘s surface and determine the entire organism‘s response to the implanted material. This work deals with the influence of the morphology and chemical composition of polyester nanofibrous materials on the adsorption of proteins. The materials produced by electrospinning (DC spinning) were characterised from the point of view of morphology and wettability. Then, the adsorption of weakly and strongly bound proteins on the fibre surface was evaluated. Cell adhesion and proliferation on the tested materials were also observed. The results of protein adsorption were compared with the results of cell adhesion and proliferation to determine the effect of the amount of adsorbed proteins on the interaction of cells with the tested materials.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
20500 - Materials engineering
Result continuities
Project
<a href="/en/project/EH22_008%2F0004562" target="_blank" >EH22_008/0004562: Excellent Research in Regenerative Medicine</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
NANOCON 2023 - Conference Proceedings, 15th International Conference on Nanomaterials
ISBN
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ISSN
2694-930X
e-ISSN
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Number of pages
8
Pages from-to
290-297
Publisher name
Moravapress s.r.o.
Place of publication
Ostrava
Event location
Brno
Event date
Jan 1, 2023
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
001234125400047