Benefits of Polyamide Nanofibrous Materials: Antibacterial Activity and Retention Ability for Staphylococcus Aureus

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24510%2F21%3A00008726" target="_blank" >RIV/46747885:24510/21:00008726 - isvavai.cz</a>

Alternative codes found

RIV/60461373:22330/21:43923681

Result on the web

<a href="https://www.mdpi.com/2079-4991/11/2/480" target="_blank" >https://www.mdpi.com/2079-4991/11/2/480</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/nano11020480" target="_blank" >10.3390/nano11020480</a>

Result language

angličtina

Original language name

Benefits of Polyamide Nanofibrous Materials: Antibacterial Activity and Retention Ability for Staphylococcus Aureus

Original language description

Although nanomaterials are used in many fields, little is known about the fundamental interactions between nanomaterials and microorganisms. To test antimicrobial properties and retention ability, 13 electrospun polyamide (PA) nanomaterials with different morphology and functionalization with various concentrations of AgNO3 and chlorhexidine (CHX) were analyzed. Staphylococcus aureus CCM 4516 was used to verify the designed nanomaterials' inhibition and permeability assays. All functionalized PAs suppressed bacterial growth, and the most effective antimicrobial nanomaterial was evaluated to be PA 12% with 4.0 wt% CHX (inhibition zones: 2.9 /- 0.2 mm; log(10) suppression: 8.9 /- 0.0; inhibitory rate: 100.0%). Furthermore, the long-term stability of all functionalized PAs was tested. These nanomaterials can be stored at least nine months after their preparation without losing their antibacterial effect. A filtration apparatus was constructed for testing the retention of PAs. All of the PAs effectively retained the filtered bacteria with log(10) removal of 3.3-6.8 and a retention rate of 96.7-100.0%. Surface density significantly influenced the retention efficiency of PAs (p = 0.05). Due to their stability, retention, and antimicrobial properties, they can serve as a model for medical or filtration applications.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

21001 - Nano-materials (production and properties)

Project

—

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nanomaterials

ISSN

2079-4991

e-ISSN

—

Volume of the periodical

11

Issue of the periodical within the volume

2

Country of publishing house

CH - SWITZERLAND

Number of pages

17

Pages from-to

480-496

UT code for WoS article

000622901200001

EID of the result in the Scopus database

2-s2.0-85100748813