Fluorine polymer probes for magnetic resonance imaging: quo vadis?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24530%2F19%3A00006470" target="_blank" >RIV/46747885:24530/19:00006470 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/s10334-018-0724-6" target="_blank" >http://dx.doi.org/10.1007/s10334-018-0724-6</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10334-018-0724-6" target="_blank" >10.1007/s10334-018-0724-6</a>
Alternative languages
Result language
angličtina
Original language name
Fluorine polymer probes for magnetic resonance imaging: quo vadis?
Original language description
Over the last few years, the development and relevance of 19 F magnetic resonance imaging (MRI) for use in clinical practice has emerged. MRI using fluorinated probes enables the achievement of a specific signal with high contrast in MRI images. However, to ensure sufficient sensitivity of 19 F MRI, fluorine probes with a high content of chemically equivalent fluorine atoms are required. The majority of 19 F MRI agents are perfluorocarbon emulsions, which have a broad range of applications in molecular imaging, although the content of fluorine atoms in these molecules is limited. In this review, we focus mainly on polymer probes that allow higher fluorine content and represent versatile platforms with properties tailorable to a plethora of biomedical in vivo applications. We discuss the chemical development, up to the first imaging applications, of these promising fluorine probes, including injectable polymers that form depots that are intended for possible use in cancer therapy.
Czech name
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Czech description
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Classification
Type
J<sub>SC</sub> - Article in a specialist periodical, which is included in the SCOPUS database
CEP classification
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OECD FORD branch
30224 - Radiology, nuclear medicine and medical imaging
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Magnetic Resonance Materials in Physics, Biology and Medicine
ISSN
1352-8661
e-ISSN
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Volume of the periodical
32
Issue of the periodical within the volume
1
Country of publishing house
DE - GERMANY
Number of pages
13
Pages from-to
173-185
UT code for WoS article
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EID of the result in the Scopus database
2-s2.0-85057805912