Chromatography-free synthesis of 2A,2B-disulfonated β-cyclodextrin for regiospecific di-substitution
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F46747885%3A24620%2F25%3A00012618" target="_blank" >RIV/46747885:24620/25:00012618 - isvavai.cz</a>
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0144861724011524" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0144861724011524</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.carbpol.2024.122926" target="_blank" >10.1016/j.carbpol.2024.122926</a>
Alternative languages
Result language
angličtina
Original language name
Chromatography-free synthesis of 2A,2B-disulfonated β-cyclodextrin for regiospecific di-substitution
Original language description
Cyclodextrins and their derivatives have extensive applications across pharmaceuticals, cosmetics, and the food industry due to their unique hydrophobic cavities. While monosubstituted cyclodextrin derivatives have established synthesis protocols, di-substituted derivatives pose significant challenges, including low yields and complex purification processes. This study presents a novel methodology for synthesizing di-substituted cyclodextrin derivatives, achieving a 33 % yield without relying on chromatographic techniques. This new approach streamlines the synthesis and purification process, making it more practical for large-scale applications and enhancing the utility of cyclodextrin derivatives in various industries.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10401 - Organic chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2025
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Carbohydrate Polymers
ISSN
0144-8617
e-ISSN
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Volume of the periodical
348
Issue of the periodical within the volume
January
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
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UT code for WoS article
001349680900001
EID of the result in the Scopus database
2-s2.0-85207551224