The Prevalence of Low Scores in the Neuropsychological Battery of Czech Brain Aging Study, the Differences Between Cognitively Healthy Adults, Subjective Cognitive Decline and Mild Cognitive Impairment due to Alzheimer’s Disease

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F47122099%3A_____%2F19%3AN0000002" target="_blank" >RIV/47122099:_____/19:N0000002 - isvavai.cz</a>

Result on the web

<a href="https://www.the-ins.org/meetings/ny2019/" target="_blank" >https://www.the-ins.org/meetings/ny2019/</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

The Prevalence of Low Scores in the Neuropsychological Battery of Czech Brain Aging Study, the Differences Between Cognitively Healthy Adults, Subjective Cognitive Decline and Mild Cognitive Impairment due to Alzheimer’s Disease

Original language description

Objective: The identification of neuropsychological impairment often involves administration and interpretation of several tests that are designed to evaluate different components of cognitive functioning. However, when interpreting multiple measures of the tests, clinicians know that a certain proportion of subjects will invariably perform some low scores. This study presents the prevalence of low scores in the Neuropsychological Battery of Czech Brain Aging Study (NB-CBAS) in cognitively healthy adults (HA) and two clinical groups: participants with Subjective Cognitive Decline (SCD) and Mild Cognitive Impairment due to Alzheimer’s Disease (AD-MCI). Participants and Methods: We examined 50 HA, 61 SCD, and 60 AD-MCI. All subjects were recruited at the Memory Disorder Clinic at Motol University Hospital in Prague. The exploratory data analysis of the prevalence of low scores focused on 15 main test scores of NB-CBAS. Results were presented in T-scores for different age and education groups. T-scores with the mean value of 50 and the standard deviation of 10 were based on rank scores of original data, i.e. they were calculated non-parametrically. The base rates of low scores were calculated for four cutoffs (-0.5 SD, -1 SD, -1.5 SD, -2 SD). Results: There were substantial differences between age and education groups in HA, SCD, and AD-MCI in case of all cut-offs. With the increasing age, the effect of the education slightly decreased. When all 15 test scores of NB-CBAS battery were considered simultaneously, AD-MCI had the highest percentage of low scores in all cut-offs. SCD and HA differed only in the cut-off -0.5SD, SCD had a higher percentage of low scores than HA. Conclusions: We confirm a fair prevalence of low scores in all groups. The prevalence increases with higher age and lower education, the highest prevalence of low scores were in AD-MCI group, and SCD differ from HA only in the cut-off -0.5SD. It seems that the prevalence of low scores could be understood as the early sign of cognitive diminishment in SCD.

Czech name

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Czech description

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Type

O - Miscellaneous

CEP classification

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OECD FORD branch

50101 - Psychology (including human - machine relations)

Project

<a href="/en/project/GA18-26094S" target="_blank" >GA18-26094S: Emotional creativity and cognitive decline in the elderly</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů