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A model of tissue perfusion based on homogenization of Darcy flow in double-porous layered medium

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F11%3A43897259" target="_blank" >RIV/49777513:23520/11:43897259 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    A model of tissue perfusion based on homogenization of Darcy flow in double-porous layered medium

  • Original language description

    We developed a model of homogenized perfusion in a medium constituted by several transversely partially periodic layers, which enables us to approximate flow through different hierarchies of the porosity. We focus on modeling the perfusion of tissue parenchyma, being motivated by medical applications: a) the assessment of the local cerebral blood flow and b) the liver segmentation. At the level of small vessels and microvessels, the perfusion can be described using the Darcy flow in double porous structure consisting of 3 compartments: two mutually disconnected channels (small arteries and veins) and the matrix (microvessels and capillaries), represented as the dual porosity, where the permeability is decreasing with the scale parameter.

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    BK - Liquid mechanics

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA106%2F09%2F0740" target="_blank" >GA106/09/0740: Microstructure oriented hierarchical modeling of brain perfusion for CT based cerebral blood flow evaluation</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2011

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů