Microscopic structural analysis of biological tissues and biomaterials
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F16%3A43930274" target="_blank" >RIV/49777513:23520/16:43930274 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Microscopic structural analysis of biological tissues and biomaterials
Original language description
The aim of this contribution is to provide practical examples on quantification of inner structures of biological tissue samples and biomaterials. Biological tissues are three dimensional composite materials produced by biological organisms. The tissues are made of cells and extracellular matrix. The matrix is composed of fibrillar proteins, such as elastin and various types of collagen, and ground substance, which contains mostly highly hydrophilic glycosaminoglycans. Moreover, most of the tissues contain blood microvessels, namely arterioles, metarterioles, precapillaries, capillaries, and postcapillary venules. Although the theoretical resolution of optical microscopy is approx. 200 nm, routine examination of biological tissues can provide morphometric data on structures ranging typically between 1-10,000 ?m. Biomaterials are engineered substances manufactured to interact with biological cells, tissues and organs to provide mechanical support, to accelerate healing, to release drugs or to serve a diagnostic purpose [10]. Both structural and mechanical properties of biological tissues and supporting biomaterials are often evaluated together. A number of stereological methods [1,2,11,12] are available for statistical determination of the geometric properties of the evaluated structures and objects, using various test probes applied to tissue sections.
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
EA - Morphology and cytology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/LO1506" target="_blank" >LO1506: Sustainability support of the centre NTIS - New Technologies for the Information Society</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2016
Confidentiality
C - Předmět řešení projektu podléhá obchodnímu tajemství (§ 504 Občanského zákoníku), ale název projektu, cíle projektu a u ukončeného nebo zastaveného projektu zhodnocení výsledku řešení projektu (údaje P03, P04, P15, P19, P29, PN8) dodané do CEP, jsou upraveny tak, aby byly zveřejnitelné.