A genetic programming-based regression for extrapolating a blood glucose-dynamics model from interstitial glucose measurements and their derivatives

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F19%3A43954250" target="_blank" >RIV/49777513:23520/19:43954250 - isvavai.cz</a>

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S1568494619300249" target="_blank" >https://www.sciencedirect.com/science/article/pii/S1568494619300249</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.asoc.2019.01.020" target="_blank" >10.1016/j.asoc.2019.01.020</a>

Result language

angličtina

Original language name

A genetic programming-based regression for extrapolating a blood glucose-dynamics model from interstitial glucose measurements and their derivatives

Original language description

This paper illustrates the development and the applicability of an Evolutionary Computation approach to enhance the treatment of Type-1 diabetic patients that necessitate insulin injections. In fact, being such a disease associated to a malfunctioning pancreas that generates an insufficient amount of insulin, a way to enhance the quality of life of these patients is to implement an artificial pancreas able to artificially regulate the insulin dosage. This work aims at extrapolating a regression model, capable of estimating the blood glucose (BG) through interstitial glucose (IG) measurements and their numerical first derivatives. Such an approach represents a viable preliminary stage in building the basic component of this artificial pancreas. In particular, considered the high complexity of the reciprocal interactions, an evolutionary-based strategy is outlined to extrapolate a mathematical relationship between BG and IG and its derivative. The investigation is carried out about the accuracy of personalized models and of a global relationship model for all of the subjects under examination. The discovered models are assessed through a comparison with other models during the experiments on personalized and global data.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10201 - Computer sciences, information science, bioinformathics (hardware development to be 2.2, social aspect to be 5.8)

Project

<a href="/en/project/LO1506" target="_blank" >LO1506: Sustainability support of the centre NTIS - New Technologies for the Information Society</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Applied Soft Computing Journal

ISSN

1568-4946

e-ISSN

—

Volume of the periodical

77

Issue of the periodical within the volume

APR 2019

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

13

Pages from-to

316-328

UT code for WoS article

000462042200024

EID of the result in the Scopus database

2-s2.0-85061062477