On the relevance of boundary conditions and viscosity models in blood flow simulations in patient‐specific aorto‐coronary bypass models
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F49777513%3A23520%2F21%3A43960788" target="_blank" >RIV/49777513:23520/21:43960788 - isvavai.cz</a>
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/10.1002/cnm.3439" target="_blank" >https://onlinelibrary.wiley.com/doi/10.1002/cnm.3439</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/cnm.3439" target="_blank" >10.1002/cnm.3439</a>
Alternative languages
Result language
angličtina
Original language name
On the relevance of boundary conditions and viscosity models in blood flow simulations in patient‐specific aorto‐coronary bypass models
Original language description
Physiologically realistic results are the aim of every blood flowsimulation. This is not different in aorto‐coronary bypasses where the properties of the coronary circulation may significantly affect the relevance of the performed simulations. By considering three patient‐specific bypass geometries, the present paper focuses on two aspects of the coronary blood flow—its phasic flow pattern and its behaviour affected by blood rheology. For the phasic flow property, a multiscale modelling approach is chosen as a means to assess the ability of five different types of coronary boundary conditions (mean arterial pressure, Windkessel model and three lumped parameter models) to attain realistic coronary hemodynamics. From the analysed variants of boundary conditions, the best option in terms of physiological characteristics and its potential for use in patient‐based simulations, is utilised to account for the effect of shear‐dependent viscosity on the resulting hemodynamics and wall shear stress stimulation. Aside from the Newtonian model, the blood rheology is approximated by two non‐Newtonian models in order to determine whether the choice of a viscosity model is important in simulations involving coronary circulation. A comprehensive analysis of obtained results demonstrated notable superiority of all lumped parameter models, especially in comparison to the constant outlet pressure, which regardless of bypass type gave overestimated and physiologically misleading results. In terms of rheology, it was noted that blood in undamaged coronary arteries behaves as a Newtonian fluid, whereas in vessels with atypical lumen geometry, such as that of anastomosis or stenosis, its shear‐thinning behaviour should not be ignored.
Czech name
—
Czech description
—
Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
20302 - Applied mechanics
Result continuities
Project
<a href="/en/project/EF17_048%2F0007280" target="_blank" >EF17_048/0007280: Application of Modern Technologies in Medicine and Industry</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal for Numerical Methods in Biomedical Engineering
ISSN
2040-7939
e-ISSN
—
Volume of the periodical
37
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
30
Pages from-to
—
UT code for WoS article
000613994300001
EID of the result in the Scopus database
2-s2.0-85100234064