Advances in chronohaematology

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F08%3A00009098" target="_blank" >RIV/60076658:12110/08:00009098 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Advances in chronohaematology

Original language description

The circadian rhythms of the haemato-immune system seem to be synchronized by two clocks: the hypothalamic endogenous, and the exogenous which is based on environmental stimuli. The suprachiasmatic nucleus is not only a circadian clock, it also synchronizes peripheral oscillators and integrates light information through the retino-hypothalamic tract. The role of the ?peripheral? clock genes in mature leucocytes still remains an unanswered question as well as the role of clock proteins in ?non-clock? physiology. The circadian rhythms may be a basis for circannual variations, although the molecular bases of such rhythms remain a mystery. There are several hormones which have a significant impact on haematological characteristics; the finding of a lower superoxide release from granulocytes at higher melatonin levels opens up new research opportunities for melatonin therapy. Discrepancies between circadian changes in mRNAs and the appropriate protein participating in haemocoagulation and f

Czech name

Pokroky v chronohematologii

Czech description

Přehledný článek věnovaný pokrokům v chronohematologii v posledních letech. Jsou nastoleny otázky týkající se hematoimunitního systému, jeho regulace na urovni celého organismu i na úrovn aktivity genů. Problematika regulace biorytmů při hemokoagulaci afibrinolýze zůstává stále ve velké míře neobjasněna. Endogenní složka rytmů usnadňuje reparativní procesy během subjektivní noci.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

FD - Oncology and haematology

OECD FORD branch

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Project

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Continuities

V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Publication year

2008

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Applied Biomedicine

ISSN

1214-021X

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

2

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

8

Pages from-to

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UT code for WoS article

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EID of the result in the Scopus database

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