Does preclinical testing on insects help to predict human myelotoxic potentials?
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F08%3A00009099" target="_blank" >RIV/60076658:12110/08:00009099 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Does preclinical testing on insects help to predict human myelotoxic potentials?
Original language description
No alternative model for human peripheral blood cells still has been found. With respect to our previous studies on insect immunotoxicological reactions we compared the morphology of human circulating blood cells and insect haemocytes using standard haematological methods. We documented that insect prohaemocytes, granulocytes and plasmatocytes have morphology which is similar to human mature lymphocytes, neutrophil granulocytes and monocytes. It offers to start studies carried on haemocytes to be evaluated as a prospective inexpensive model for toxicological praescreening.
Czech name
Pomáhá preklinické testování na hmyzu predikci lidského myelotoxického potenciálu?
Czech description
Přehledný článek diskutující podobnost hemocytů a cirkulujících krvinek v rozsahu základních hematologických metod při vývoji biomodelů pro toxikologický preskríning.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2008
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
AATEX
ISSN
1344-0411
e-ISSN
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Volume of the periodical
14
Issue of the periodical within the volume
SI
Country of publishing house
JP - JAPAN
Number of pages
3
Pages from-to
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UT code for WoS article
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EID of the result in the Scopus database
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