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Does preclinical testing on insects help to predict human myelotoxic potentials?

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F08%3A00009099" target="_blank" >RIV/60076658:12110/08:00009099 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Does preclinical testing on insects help to predict human myelotoxic potentials?

  • Original language description

    No alternative model for human peripheral blood cells still has been found. With respect to our previous studies on insect immunotoxicological reactions we compared the morphology of human circulating blood cells and insect haemocytes using standard haematological methods. We documented that insect prohaemocytes, granulocytes and plasmatocytes have morphology which is similar to human mature lymphocytes, neutrophil granulocytes and monocytes. It offers to start studies carried on haemocytes to be evaluated as a prospective inexpensive model for toxicological praescreening.

  • Czech name

    Pomáhá preklinické testování na hmyzu predikci lidského myelotoxického potenciálu?

  • Czech description

    Přehledný článek diskutující podobnost hemocytů a cirkulujících krvinek v rozsahu základních hematologických metod při vývoji biomodelů pro toxikologický preskríning.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    FP - Other medical fields

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    V - Vyzkumna aktivita podporovana z jinych verejnych zdroju

Others

  • Publication year

    2008

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    AATEX

  • ISSN

    1344-0411

  • e-ISSN

  • Volume of the periodical

    14

  • Issue of the periodical within the volume

    SI

  • Country of publishing house

    JP - JAPAN

  • Number of pages

    3

  • Pages from-to

  • UT code for WoS article

  • EID of the result in the Scopus database