Palytoxin
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F18%3A43897807" target="_blank" >RIV/60076658:12110/18:43897807 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Palytoxin
Original language description
Palytoxin (PLTX) is a lethal, heat-stable marine toxin, which was first isolated in 1971 in Hawaii from the seaweed-like coral, Limu-make-o-Hana (Seaweed of Death from Hana), polyps of the genus Palythoa [2]. Later identified as Palythoa toxica, a zoanthid of the tropical areas of the Pacific Ocean, PLTX is a marine polyalcohol toxin with a very large and complex chemical structure that has both lipophilic and hydrophilic moieties. PLTX and its analogues have been implicated in toxic events in humans following ingestion, dermal exposure, or inhalation of vapors, and in animals following various routes of administration [4]. Moreover, PLTX and its analogues exert their potent biological activity by altering normal ion homeostasis in excitable and nonexcitable tissues. The toxin depolarizes mammalian cells by causing cation conductance with relatively low ion selectivity.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30108 - Toxicology
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Handbook of Foodborne Diseases
ISBN
978-1-138-03630-7
Number of pages of the result
7
Pages from-to
1035-1041
Number of pages of the book
1192
Publisher name
CRC Press
Place of publication
Spojené státy americké
UT code for WoS chapter
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