Pharmacological management of osteoporosis in nursing home residents: the Shelter study

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12110%2F21%3A43902126" target="_blank" >RIV/60076658:12110/21:43902126 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11110/21:10420342

Result on the web

<a href="https://www.sciencedirect.com/science/article/pii/S0378512220304205?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0378512220304205?via%3Dihub</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.maturitas.2020.10.020" target="_blank" >10.1016/j.maturitas.2020.10.020</a>

Result language

angličtina

Original language name

Pharmacological management of osteoporosis in nursing home residents: the Shelter study

Original language description

Objective: To prevent osteoporotic fractures in nursing home residents a combination of bisphosphonates, calcium and vitamin D is recommended. This study assessed the prevalence of pharmacological osteoporosis prevention in nursing home residents from eight countries, and assessed its association with patient characteristics.Design: Cross-sectional analyses of the SHELTER study data. We assessed the overall prevalence of osteoporosis medication (OM) use (vitamin D, calcium and bisphosphonates) in residents stratified for falls and fractures over last 30 days, health instability with high mortality risk, cognitive impairment, and dependence in walking. Setting and Participants: Nursing home residents in the Czech Republic, England, Finland, France, Germany, Italy, The Netherlands and Israel. Results: Of 3832 eligible residents, vitamin D, calcium and bisphosphonates were used by 16.2%, 10.4%, and 4.5% respectively. All 3 classes of OM together were used by 1.5% of all residents. Of residents with a recent fracture, 9.5% used a bisphosphonate (2.7% all 3 OMs). In patients with recent falls, 20.8% used vitamin D and 15.3% calcium. In residents with severe cognitive impairment, 15.5% used vitamin D and 9.3% used calcium. Of the bisphosphonate users, 33.7% also used both vitamin D and calcium, 25.8% used only calcium in addition and 17.4% only vitamin D in addition. The use of any OM varied widely across countries, from 66.8% in Finland to 3.0% in Israel. Conclusions and Implications: We found substantial pharmacological under-treatment of prevention of osteoporosis in residents with recent falls, fractures and dependence in walking. Only two-thirds of bisphosphonate users also took a vitamin D–calcium combination, despite guideline recommendations. On the other hand, possible over-treatment was found in residents with high mortality risk in whom preventive pharmacotherapy might not have still been appropriate. The prevalence of pharmacological prevention of osteoporosis differed substantially between countries. Efforts are needed to improve pharmacotherapy in residents.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30307 - Nursing

Project

<a href="/en/project/7E09071" target="_blank" >7E09071: Services and Health for Elderly in Long TERm care</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Maturitas

ISSN

0378-5122

e-ISSN

—

Volume of the periodical

143

Issue of the periodical within the volume

January 2021

Country of publishing house

IE - IRELAND

Number of pages

6

Pages from-to

184-189

UT code for WoS article

000600575100026

EID of the result in the Scopus database

2-s2.0-85094976093