Genotyping Glycogen Storage Disease Type II and Type V in Cattle Reared in the Czech Republic

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12220%2F07%3A00008180" target="_blank" >RIV/60076658:12220/07:00008180 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12220/07:8P001640 RIV/00027162:_____/07:#0000447

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Genotyping Glycogen Storage Disease Type II and Type V in Cattle Reared in the Czech Republic

Original language description

Genotyping was carried out for glycogen storage disease type II and type V in seven cattle breeds. The analysis was carried out using the polymerase chain reaction/restriction fragment length polymorphism (PCR/RFLP) method. In the breeds analysed (Charolais, Czech Spotted - Czech Simmental, Belgian Blue, Limousine, Blonde d'Aquitaine, Aberdeen Angus and beef Simmental sires reared in the Czech Republic), the recessive allele was not found in the PYGM (phosphorylase glycogen, muscle) responsible for theglycogen storage disease type V. In the same apnel, the recessive allele in exon 7, exon 9 and exon 13 of the GAA (glucosidase alpha, acid), causing the glycogen storage disease type II was not found. Therefore, we have not revealed the recessive outsideprevious reported breeds. The knowledge of the breed specific occurrence of inherited disorders facilitates focusing and reduces the costs of detecting the heterozygous carriers of recessive inherited disorders.

Czech name

Genotypizace glycogen storage disease typu II a typu V u skotu chovaného v České republice

Czech description

U sedmi plemen skotu jsme genotypizovali lokus pro glycogen storage disease typu II a typu V. Analýza byla provedena s využitím PCR/RFLP. U býků plemen charolais, české strakaté, belgické modré, limousin, plavé akvitánské, aberdeen angus a masný simentáljsme nenalezli recesivní alelu PYGM (phosphorylase glycogen, muscle) zodpovědnou za glycogen storage disease typu V. Ve stejném panelu nebyla nalezena ani recesivní alela GAA (glucosidase alpha, acid) v exonu 7, 9 a 13, která zapříčiňuje vznik glycogenstorage disease typu II. U analyzovaných plemen jsme tedy nenalezli žádné skryté přenašeče. Znalost plemenně specifického výskytu dědičných chorob usnadňuje zaměření a redukuje náklady na detekci heterozygotních přenašečů recesivně podmíněných dědičnýchchorob.

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2007

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Veterinary Medicine Series A

ISSN

0931-184X

e-ISSN

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Volume of the periodical

54

Issue of the periodical within the volume

5

Country of publishing house

GB - UNITED KINGDOM

Number of pages

3

Pages from-to

257-259

UT code for WoS article

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EID of the result in the Scopus database

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