Chronic dietary toxicity of zinc oxide nanoparticles in common carp (Cyprinus carpio L.): Tissue accumulation and physiological responses

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12220%2F18%3A43895996" target="_blank" >RIV/60076658:12220/18:43895996 - isvavai.cz</a>

Alternative codes found

RIV/60076658:12520/18:43895996 RIV/61989592:15310/18:73588050

Result on the web

<a href="https://ac.els-cdn.com/S0147651317305195/1-s2.0-S0147651317305195-main.pdf?_tid=5a5c2bec-029a-11e8-bf59-00000aab0f6b&acdnat=1516972440_2f160b17f7a61beb7983048ec78b8cf8" target="_blank" >https://ac.els-cdn.com/S0147651317305195/1-s2.0-S0147651317305195-main.pdf?_tid=5a5c2bec-029a-11e8-bf59-00000aab0f6b&acdnat=1516972440_2f160b17f7a61beb7983048ec78b8cf8</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ecoenv.2017.08.024" target="_blank" >10.1016/j.ecoenv.2017.08.024</a>

Result language

angličtina

Original language name

Chronic dietary toxicity of zinc oxide nanoparticles in common carp (Cyprinus carpio L.): Tissue accumulation and physiological responses

Original language description

Concerns regarding the potential toxic effects of zinc oxide nanoparticles (ZnO NPs) on aquatic organisms are growing due to the fact that NPs may be released into aquatic ecosystems. This study aimed to investigate the effects of dietary exposure to ZnO NPs on juvenile common carp (Cyprinus carpio). Fish were fed a spiked diets at doses 50 and 500 mg of ZnO NPs per kg of feed for 6 weeks followed by a 2-week recovery period. Fish were sampled every 2 weeks for haematology trends, blood biochemistry measures, histology analyses, and determination of the accumulation of zinc in tissues. At the end of the exposure and post-exposure periods, fish were sampled for an assessment of lipid peroxidation levels. Dietborne ZnO NPs had no effects on haematology, blood biochemistry, and lipid peroxidation levels during the exposure period. After the recovery period, aspartate aminotransferase activity significantly (p &lt; 0.05) increased and alanine transferase activity significantly (p &lt; 0.05) decreased in the higher exposure group. The level of lipid peroxidation significantly (p &lt; 0.05) decreased in liver of treated fish after 2 weeks post-exposure period. A histological examination revealed mild histopathological changes in kidneys during exposure. Our results did not show a significant increase of zinc content at the end of experiment in any of tested organs. However, chronic dietary exposure to ZnO NPs might affect kidney and liver function.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10511 - Environmental sciences (social aspects to be 5.7)

Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Ecotoxicology and Environmental Safety

ISSN

0147-6513

e-ISSN

—

Volume of the periodical

147

Issue of the periodical within the volume

1/2018

Country of publishing house

US - UNITED STATES

Number of pages

7

Pages from-to

110-116

UT code for WoS article

000416199700015

EID of the result in the Scopus database

2-s2.0-85027846751