A Candidate Gene Association Study for Economically Important Traits in Czech Dairy Goat Breeds

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12220%2F21%3A43902926" target="_blank" >RIV/60076658:12220/21:43902926 - isvavai.cz</a>

Alternative codes found

RIV/00027014:_____/21:N0000079 RIV/00027162:_____/21:N0000089

Result on the web

<a href="https://doi.org/10.3390/ani11061796" target="_blank" >https://doi.org/10.3390/ani11061796</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/ani11061796" target="_blank" >10.3390/ani11061796</a>

Result language

angličtina

Original language name

A Candidate Gene Association Study for Economically Important Traits in Czech Dairy Goat Breeds

Original language description

Simple Summary The milk production traits of goats are economically important. In the Czech Republic, goat milk is processed directly on farms and distributed as cheese. Although goat breeding is not a main focus of animal production in the Czech Republic, it is essential for the agricultural sector. A group of 14 SNPs (single-nucleotide polymorphisms) within four candidate genes (ACACA, BTN1A1, LPL, and SCD) were analysed in two Czech dairy goat breeds, White Shorthaired (WSH) goats and Brown Shorthaired (BSH) goats. The SNPs were significantly associated with milk-production traits (daily milk yield, protein, and fat percentage) and somatic cell count. This information may be useful for marker-assisted selection or related techniques to increase the accuracy of selection. Milk production is influenced by many factors, including genetic and environmental factors and their interactions. Animal health, especially udder health, is usually evaluated by the number of somatic cells. The present study described the effect of polymorphisms in the ACACA, BTN1A1, LPL, and SCD genes on the daily milk yield, fat, and protein percentages and somatic cell count. In this study, 590 White Shorthaired (WSH) and Brown Shorthaired (BSH) goats were included. SNP genotyping was performed by PCR-RFLP and multiplex PCR followed by SNaPshot minisequencing analysis. The linear mixed model with repeated measurement was used to identify the genetic associations between the studied genes/SNPs and chosen traits. All selected genes were polymorphic in the tested goat populations and showed significant associations with milk traits. Only BTN1A1 (SNP g.599 A &gt; G) showed a significant association with the somatic cell score. After Bonferroni correction, a significant effect of LPL g.300G &gt; A on daily milk yield and fat percentage, LPL g.185G &gt; T on protein percentage, and LPL G50C, SCD EX3_15G &gt; A, and SCD EX3_68A &gt; G on fat percentage was found. The importance of environmental factors, such as the herd-year effect, month of milking, and lactation order on all milk performance indicators was confirmed.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

40101 - Agriculture

Project

<a href="/en/project/QK1910320" target="_blank" >QK1910320: Research of dairy cattle breeding methods with the goal to improve disease resistance using genomic approach, systemic health data collecting and targeted genotyping</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Animals

ISSN

2076-2615

e-ISSN

—

Volume of the periodical

11

Issue of the periodical within the volume

6

Country of publishing house

CH - SWITZERLAND

Number of pages

15

Pages from-to

1796

UT code for WoS article

000665477900001

EID of the result in the Scopus database

—