Antibacterial Activity and Chemical Composition of Popular Plant Essential Oils and Their Positive Interactions in Combination

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12220%2F25%3A43911306" target="_blank" >RIV/60076658:12220/25:43911306 - isvavai.cz</a>

Result on the web

<a href="https://www.mdpi.com/1420-3049/30/9/1864" target="_blank" >https://www.mdpi.com/1420-3049/30/9/1864</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.3390/molecules30091864" target="_blank" >10.3390/molecules30091864</a>

Result language

angličtina

Original language name

Antibacterial Activity and Chemical Composition of Popular Plant Essential Oils and Their Positive Interactions in Combination

Original language description

Bacterial diseases are a global problem that threatens human health and cause many deaths each year. The alarming rise in bacterial resistance to modern antimicrobials is particularly concerning. In practice, this necessitates increasing the dosage of antimicrobial agents, posing a potential risk of adverse effects on human health. Additionally, the development of antibiotic resistance is one of the main factors contributing to the ever-growing costs of the global healthcare system. For these reasons, natural and safe antimicrobial agents are increasingly sought after. In this study, the antibacterial activity of 31 different essential oils (EOs) was investigated against Escherichia coli and Staphylococcus aureus. The most effective EOs were further tested both individually and in dual combinations. Minimum inhibitory concentrations (MICs) and fractional inhibitory concentrations (FICs) were determined to reveal synergistic effects, suggesting potential practical applications. The main bioactive compounds of the EOs with the highest inhibitory activity were identified and quantified using GC-MS/MS analysis. Of the tested EOs, seven demonstrated a strong antimicrobial effect against E. coli, most notably oregano (MIC 128 mu g/mL) and the thyme/oregano combination (MIC 64 mu g/mL, FIC 0.75), while thirteen were effective against S. aureus, most notably oregano and garlic (MIC 128 mu g/mL),and the pelargonium/garlic combination (MIC 32 mu g/mL, FIC 0.375). The pharmaceutical, agricultural, and food industries are promising fields for the application of these safe and natural antimicrobial agents, offering a new range of solutions to combat serious bacterial pathogens.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

10608 - Biochemistry and molecular biology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Molecules

ISSN

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e-ISSN

1420-3049

Volume of the periodical

30

Issue of the periodical within the volume

9

Country of publishing house

CH - SWITZERLAND

Number of pages

16

Pages from-to

nestránkováno

UT code for WoS article

001486457900001

EID of the result in the Scopus database

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