Systematically fragmented genes in a multipartite mitochondrial genome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F11%3A43872221" target="_blank" >RIV/60076658:12310/11:43872221 - isvavai.cz</a>

Alternative codes found

RIV/60077344:_____/11:00356039 RIV/68378050:_____/11:00356039

Result on the web

<a href="http://dx.doi.org/10.1093/nar/gkq883" target="_blank" >http://dx.doi.org/10.1093/nar/gkq883</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1093/nar/gkq883" target="_blank" >10.1093/nar/gkq883</a>

Result language

angličtina

Original language name

Systematically fragmented genes in a multipartite mitochondrial genome

Original language description

Arguably, the most bizarre mitochondrial DNA (mtDNA) is that of the euglenozoan eukaryote Diplonema papillatum. The genome consists of numerous small circular chromosomes none of which appears to encode a complete gene. For instance, the cox1 coding sequence is spread out over nine different chromosomes in non-overlapping pieces (modules), which are transcribed separately and joined to a contiguous mRNA by trans-splicing. Here, we examine how many genes are encoded by Diplonema mtDNA and whether all arefragmented and their transcripts trans-spliced. Module identification is challenging due to the sequence divergence of Diplonema mitochondrial genes. By employing most sensitive protein profile search algorithms and comparing genomic with cDNA sequence,we recognize a total of 11 typical mitochondrial genes. The 10 protein-coding genes are systematically chopped up into three to 12 modules of 60-350 bp length. The corresponding mRNAs are all trans-spliced. Identification of ribosomal RN

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EB - Genetics and molecular biology

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2011

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Nucleic Acids Research

ISSN

0305-1048

e-ISSN

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Volume of the periodical

39

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

10

Pages from-to

979-988

UT code for WoS article

000287257500024

EID of the result in the Scopus database

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