Oxidative stress elicited by insecticides: A role for the adipokinetic hormone

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F11%3A43882918" target="_blank" >RIV/60076658:12310/11:43882918 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/j.ygcen.2010.12.009" target="_blank" >http://dx.doi.org/10.1016/j.ygcen.2010.12.009</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ygcen.2010.12.009" target="_blank" >10.1016/j.ygcen.2010.12.009</a>

Result language
angličtina
Original language name
Oxidative stress elicited by insecticides: A role for the adipokinetic hormone
Original language description
Adipokinetic hormones (AKHs) are insect neuropetides responding to stress situations including oxidative stress. Two insecticides - endosulfan and malathion - were used to elicit oxidative stress conditions in the firebug Pyrrhocoris apterus, and the physiological functions of AKHs and their ability to activate protective antioxidative reactions were studied. The insecticide treatments elicited only a slight increase of the AKH level in CNS, but more intensive increase in haemolymph, which indicates animmediate involvement of AKH in the stress response. The treatment also resulted in a significant increase of catalase activity in the bug's body and depletion of the reduced glutathione pool in the haemolymph, however, co-application of the insecticideswith the AKH (80 pmol) reduced the effect. It has also been found that co-application of the insecticides with AKH increased significantly the bug mortality compared to that induced by the insecticides alone. This enhanced effect of the
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Publication year
2011
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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