Nature's Timepiece-Molecular Coordination of Metabolism and Its Impact on Aging

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F13%3A43886437" target="_blank" >RIV/60076658:12310/13:43886437 - isvavai.cz</a>
Result on the web
<a href="http://www.mdpi.com/1422-0067/14/2/3026" target="_blank" >http://www.mdpi.com/1422-0067/14/2/3026</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/ijms14023026" target="_blank" >10.3390/ijms14023026</a>

Result language
angličtina
Original language name
Nature's Timepiece-Molecular Coordination of Metabolism and Its Impact on Aging
Original language description
Circadian rhythms are found in almost all organisms from cyanobacteria to humans, where most behavioral and physiological processes occur over a period of approximately 24 h in tandem with the day/night cycles. In general, these rhythmic processes are under regulation of circadian clocks. The role of circadian clocks in regulating metabolism and consequently cellular and metabolic homeostasis is an intensively investigated area of research. However, the links between circadian clocks and aging are correlative and only recently being investigated. A physiological decline in most processes is associated with advancing age, and occurs at the onset of maturity and in some instances is the result of accumulation of cellular damage beyond a critical level. Afully functional circadian clock would be vital to timing events in general metabolism, thus contributing to metabolic health and to ensure an increased "health-span" during the process of aging. Here, we present recent evidence of links
Czech name
—
Czech description
—

Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
—

Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)