Unique roles of glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F13%3A43886438" target="_blank" >RIV/60076658:12310/13:43886438 - isvavai.cz</a>
Result on the web
<a href="http://ac.els-cdn.com/S1095643312004904/1-s2.0-S1095643312004904-main.pdf?_tid=8548075a-9e0c-11e3-9198-00000aab0f27&acdnat=1393326416_298a2357f8ee8d90700daff01113a7b7" target="_blank" >http://ac.els-cdn.com/S1095643312004904/1-s2.0-S1095643312004904-main.pdf?_tid=8548075a-9e0c-11e3-9198-00000aab0f27&acdnat=1393326416_298a2357f8ee8d90700daff01113a7b7</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cbpa.2012.10.012" target="_blank" >10.1016/j.cbpa.2012.10.012</a>
Alternative languages
Result language
angličtina
Original language name
Unique roles of glucagon and glucagon-like peptides: Parallels in understanding the functions of adipokinetic hormones in stress responses in insects
Original language description
Glucagon is conventionally regarded as a hormone, counter regulatory in function to insulin and plays a critical anti-hypoglycemic role by maintaining glucose homeostasis in both animals and humans. Glucagon performs this function by increasing hepatic glucose output to the blood by stimulating glycogenolysis and gluconeogenesis in response to starvation. Additionally it plays a homeostatic role by decreasing glycogenesis and glycolysis in tandem to try and maintain optimal glucose levels. To perform this action, it also increases energy expenditure which is contrary to what one would expect and has actions which are unique and not entirely in agreement with its role in protection from hypoglycemia. Interestingly, glucagon-like peptides (GLP-1 and GLP-2) from the major fragment of proglucagon (in non-mammalian vertebrates, as well as in mammals) may also modulate response to stress in addition to their other physiological actions. These unique modes of action occur in response to psych
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
ED - Physiology
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2013
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Comparative Biochemistry and Physiology A-Molecular & Integrative Physiology
ISSN
1095-6433
e-ISSN
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Volume of the periodical
164
Issue of the periodical within the volume
1
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
91-100
UT code for WoS article
000312421400013
EID of the result in the Scopus database
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