Role of adipokinetic hormone during starvation in Drosophila
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F18%3A43897536" target="_blank" >RIV/60076658:12310/18:43897536 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/18:00492457
Result on the web
<a href="https://reader.elsevier.com/reader/sd/pii/S109649591830099X?token=D20B5E642F6264CC582C44D82F5DF988823D6636B5843CA0DE38DECDFF72CFC0970A5DD3A11A806F4DD01BFA4B07A440" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S109649591830099X?token=D20B5E642F6264CC582C44D82F5DF988823D6636B5843CA0DE38DECDFF72CFC0970A5DD3A11A806F4DD01BFA4B07A440</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.cbpb.2018.08.004" target="_blank" >10.1016/j.cbpb.2018.08.004</a>
Alternative languages
Result language
angličtina
Original language name
Role of adipokinetic hormone during starvation in Drosophila
Original language description
The role of adipokinetic hormone (Drome-AKH) in maintaining the levels of basic nutrients, under starvation conditions, was studied using Drosophila melanogaster mutants with AKH deficiency (Akh(1)) and AKH abundance (EE-Akh). Our results showed lipids as the main energy reserve in Drosophila, and their physiological level and metabolism were shown to be under the control of AKH. AKH abundance in the body resulted in lower levels of triacylglycerols and diacylglycerols than in the controls, probably due to a more intensive metabolism; interestingly, there was a disproportional representation of fatty acids in triacylglycerols and diacylglycerols in Drosophila. Lower level of glycogen and its partial control by AKH suggest its lesser role as the storage substance. However, maintenance of free carbohydrate level in Drosophila seemed to be critical; when glycogen stores are exhausted, carbohydrates are synthesized from other sources. Protein levels and their alterations, under starvation, did not seem controlled by AKH. AKH-deficient flies were more resistant while AKH-abundant flies were more sensitive to starvation; females were found to be more resistant than males, regardless of the AKH level, probably due to higher body mass and higher amount of nutrients. However, in accordance with the level of all nutrients, that of AKH also gradually decreased with prolonged starvation.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Comparative Biochemistry and Physiology B - Biochemistry & Molecular Biology
ISSN
1096-4959
e-ISSN
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Volume of the periodical
226
Issue of the periodical within the volume
DEC 2018
Country of publishing house
US - UNITED STATES
Number of pages
10
Pages from-to
26-35
UT code for WoS article
000447114400004
EID of the result in the Scopus database
2-s2.0-85051656925