Reservoir and vector evolutionary pressures shaped the adaptation of Borrelia

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F18%3A43897654" target="_blank" >RIV/60076658:12310/18:43897654 - isvavai.cz</a>

Alternative codes found

RIV/60077344:_____/18:00498462

Result on the web

<a href="https://reader.elsevier.com/reader/sd/pii/S1567134818301230?token=D8AD293FE0140878DC3FC69CCF45A2840FA3AF8C7E33944E2203E55B53479C7685C40EBEE1B731C21AC6C691BFB71858" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S1567134818301230?token=D8AD293FE0140878DC3FC69CCF45A2840FA3AF8C7E33944E2203E55B53479C7685C40EBEE1B731C21AC6C691BFB71858</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.meegid.2018.03.023" target="_blank" >10.1016/j.meegid.2018.03.023</a>

Result language

angličtina

Original language name

Reservoir and vector evolutionary pressures shaped the adaptation of Borrelia

Original language description

The life cycle of spirochetes of the genus Borrelia includes complex networks of vertebrates and ticks. The tripartite association of Borrelia-vertebrate-tick has proved ecologically successful for these bacteria, which have become some of the most prominent tick-borne pathogens in the northern hemisphere. To keep evolutionary pace with its double-host life history, Borrelia must adapt to the evolutionary pressures exerted by both sets of hosts. In this review, we attempt to reconcile functional, phylogenetic, and ecological perspectives to propose a coherent scenario of Borrelia evolution. Available empirical information supports that the association of Borrelia with ticks is very old. The major split between the tick families Argasidae-Ixodidae (dated some 230-290 Mya) resulted in most relapsing fever (Rf) species being restricted to Argasidae and few associated with Ixodidae. A further key event produced the diversification of the Lyme borreliosis (Lb) species: the radiation of ticks of the genus Ixodes from the primitive stock of Ixodidae (around 217 Mya). The ecological interactions of Borrelia demonstrate that Argasidae-transmitted Rf species remain restricted to small niches of one tick species and few vertebrates. The evolutionary pressures on this group are consequently low, and speciation processes seem to be driven by geographical isolation. In contrast to Rf, Lb species circulate in nested networks of dozens of tick species and hundreds of vertebrate species. This greater variety confers a remarkably variable pool of evolutionary pressures, resulting in large speciation of the Lb group, where different species adapt to circulate through different groups of vertebrates. Available data, based on ospA and multilocus sequence typing (including eight concatenated in-house genes) phylogenetic trees, suggest that ticks could constitute a secondary bottleneck that contributes to Lb specialization. Both sets of adaptive pressures contribute to the resilience of highly adaptable meta-populations of bacteria.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10608 - Biochemistry and molecular biology

Project

—

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2018

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Infection, Genetics and Evolution

ISSN

1567-1348

e-ISSN

—

Volume of the periodical

66

Issue of the periodical within the volume

DEC 2018

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

11

Pages from-to

308-318

UT code for WoS article

000452589900040

EID of the result in the Scopus database

2-s2.0-85045831745