Widespread occurrence of retinoids in water bodies associated with cyanobacterial blooms dominated by diverse species
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F19%3A43899185" target="_blank" >RIV/60076658:12310/19:43899185 - isvavai.cz</a>
Alternative codes found
RIV/00216224:14310/19:00107569
Result on the web
<a href="https://reader.elsevier.com/reader/sd/pii/S0043135419302210?token=A38DF5506228226D3BF5DFAAD9D7B4DDC5A240353B4F9AA765E9063A7EE46536378D58CF4560931B2057BE5A6C3F7C81" target="_blank" >https://reader.elsevier.com/reader/sd/pii/S0043135419302210?token=A38DF5506228226D3BF5DFAAD9D7B4DDC5A240353B4F9AA765E9063A7EE46536378D58CF4560931B2057BE5A6C3F7C81</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.watres.2019.03.009" target="_blank" >10.1016/j.watres.2019.03.009</a>
Alternative languages
Result language
angličtina
Original language name
Widespread occurrence of retinoids in water bodies associated with cyanobacterial blooms dominated by diverse species
Original language description
Cyanobacterial blooms represent a worldwide problem in freshwater as well as marine ecosystems as producers of various toxic compounds. This study provides environmentally important information about the common presence of mixtures of retinoids in various water bodies associated with the occurrence of cyanobacterial blooms dominated by many different species. The study documents, for the first time, that retinoids are produced by environmental cyanobacterial blooms dominated by species belonging to different genera such as Microcystis, Dolichospermum, Planktothrix, Woronichinia, Pseudanabaena and others. Samples of biomass of cyanobacterial blooms and their surrounding water were collected from seventeen independent freshwater bodies across the Czech Republic during summer 2015. Retinoid-like activity was detected by an in vitro reporter gene bioassay in water samples from 8 out of 17 localities with a maximal activity of 263 ng all-trans retinoic acid equivalent (REQ)/L. In comparison, in vitro assessment of biomass extracts documented retinoid-like activity at 11 out of 17 localities with a maximal retinoid-like activity of 867 ng REQ/g dry mass (dm). Individual retinoids were detected by chemical analyses in all water samples and in 16 out of 17 biomass samples with 4keto-retinal and all trans 5,6epoxy retinoic acid being detected in aquatic ecosystems for the first time. Further, all-trans 4keto retinoic acid and retinal were the most commonly detected compounds in both types of samples. With respect to retinoid-like activity, a large proportion was explained in some samples by contributions of individual detected retinoids calculated from their concentrations and relative potencies. However, results also indicate that other unknown compounds with a retinoic acid receptor-mediated mode of action were present. The revealed widespread production of retinoids by cyanobacterial blooms dominated by diverse species across various aquatic ecosystems and their common presence in both biomass and surrounding water raises concern namely because some retinoids belong to the most potent teratogens. These compounds need to be taken into consideration in the assessment of risks associated with massive cyanobacterial blooms. (C) 2019 Elsevier Ltd. All rights reserved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20701 - Environmental and geological engineering, geotechnics
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Water Research
ISSN
0043-1354
e-ISSN
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Volume of the periodical
156
Issue of the periodical within the volume
JUN 1 2019
Country of publishing house
GB - UNITED KINGDOM
Number of pages
12
Pages from-to
136-147
UT code for WoS article
000466618400013
EID of the result in the Scopus database
2-s2.0-85063224256