Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F19%3A43899520" target="_blank" >RIV/60076658:12310/19:43899520 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/19:00508104
Result on the web
<a href="https://science.sciencemag.org/content/365/6460/1457" target="_blank" >https://science.sciencemag.org/content/365/6460/1457</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1126/science.aax1318" target="_blank" >10.1126/science.aax1318</a>
Alternative languages
Result language
angličtina
Original language name
Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests
Original language description
In insects, rapidly evolving primary sex-determining signals are transduced by a conserved regulatory module controlling sexual differentiation. In the agricultural pest Ceratitis capitata (Mediterranean fruit fly, or Medfly), we identified a Y-linked gene, Maleness-on-the-Y (MoY), encoding a small protein that is necessary and sufficient for male development. Silencing or disruption of MoY in XY embryos causes feminization, whereas overexpression of MoY in XX embryos induces masculinization. Crosses between transformed XY females and XX males give rise to males and females, indicating that a Y chromosome can be transmitted by XY females. MoY is Y-linked and functionally conserved in other species of the Tephritidae family, highlighting its potential to serve as a tool for developing more effective control strategies against these major agricultural insect pests.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10616 - Entomology
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Science
ISSN
0036-8075
e-ISSN
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Volume of the periodical
365
Issue of the periodical within the volume
6460
Country of publishing house
US - UNITED STATES
Number of pages
3
Pages from-to
1457-1460
UT code for WoS article
000488838600049
EID of the result in the Scopus database
2-s2.0-85072710875