Novel targets and strategies to combat borreliosis
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F20%3A43901182" target="_blank" >RIV/60076658:12310/20:43901182 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/20:00540545
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs00253-020-10375-8" target="_blank" >https://link.springer.com/article/10.1007%2Fs00253-020-10375-8</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00253-020-10375-8" target="_blank" >10.1007/s00253-020-10375-8</a>
Alternative languages
Result language
angličtina
Original language name
Novel targets and strategies to combat borreliosis
Original language description
Lyme borreliosis is a bacterial infection that can be spread to humans by infected ticks and may severely affect many organs and tissues. Nearly four decades have elapsed since the discovery of the disease agent called Borrelia burgdorferi. Although there is a plethora of knowledge on the infectious agent and thousands of scientific publications, an effective way on how to combat and prevent Lyme borreliosis has not been found yet. There is no vaccine for humans available, and only one active vaccine program in clinical development is currently running. A spirited search for possible disease interventions is of high public interest as surveillance data indicates that the number of cases of Lyme borreliosis is steadily increasing in Europe and North America. This review provides a condensed digest of the history of vaccine development up to new promising vaccine candidates and strategies that are targeted against Lyme borreliosis, including elements of the tick vector, the reservoir hosts, and the Borrelia pathogen itself.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/GA17-21244S" target="_blank" >GA17-21244S: Delineating the role of Borreli afzelii genes required for dissemination within an infected tick during feeding</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2020
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Applied Microbiology and Biotechnology
ISSN
0175-7598
e-ISSN
—
Volume of the periodical
104
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
11
Pages from-to
1915-1925
UT code for WoS article
000507785800002
EID of the result in the Scopus database
2-s2.0-85078242119