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Novel targets and strategies to combat borreliosis

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F20%3A43901182" target="_blank" >RIV/60076658:12310/20:43901182 - isvavai.cz</a>

  • Alternative codes found

    RIV/60077344:_____/20:00540545

  • Result on the web

    <a href="https://link.springer.com/article/10.1007%2Fs00253-020-10375-8" target="_blank" >https://link.springer.com/article/10.1007%2Fs00253-020-10375-8</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1007/s00253-020-10375-8" target="_blank" >10.1007/s00253-020-10375-8</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Novel targets and strategies to combat borreliosis

  • Original language description

    Lyme borreliosis is a bacterial infection that can be spread to humans by infected ticks and may severely affect many organs and tissues. Nearly four decades have elapsed since the discovery of the disease agent called Borrelia burgdorferi. Although there is a plethora of knowledge on the infectious agent and thousands of scientific publications, an effective way on how to combat and prevent Lyme borreliosis has not been found yet. There is no vaccine for humans available, and only one active vaccine program in clinical development is currently running. A spirited search for possible disease interventions is of high public interest as surveillance data indicates that the number of cases of Lyme borreliosis is steadily increasing in Europe and North America. This review provides a condensed digest of the history of vaccine development up to new promising vaccine candidates and strategies that are targeted against Lyme borreliosis, including elements of the tick vector, the reservoir hosts, and the Borrelia pathogen itself.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database

  • CEP classification

  • OECD FORD branch

    10606 - Microbiology

Result continuities

  • Project

    <a href="/en/project/GA17-21244S" target="_blank" >GA17-21244S: Delineating the role of Borreli afzelii genes required for dissemination within an infected tick during feeding</a><br>

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2020

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Applied Microbiology and Biotechnology

  • ISSN

    0175-7598

  • e-ISSN

  • Volume of the periodical

    104

  • Issue of the periodical within the volume

    5

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    11

  • Pages from-to

    1915-1925

  • UT code for WoS article

    000507785800002

  • EID of the result in the Scopus database

    2-s2.0-85078242119