Associating physiological functions with genomic variability in hibernating bats

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F21%3A43902949" target="_blank" >RIV/60076658:12310/21:43902949 - isvavai.cz</a>
Alternative codes found
RIV/68081766:_____/21:00538410 RIV/62157124:16270/21:43879705 RIV/00216224:14310/21:00121008
Result on the web
<a href="https://link.springer.com/article/10.1007%2Fs10682-020-10096-4" target="_blank" >https://link.springer.com/article/10.1007%2Fs10682-020-10096-4</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s10682-020-10096-4" target="_blank" >10.1007/s10682-020-10096-4</a>

Result language
angličtina
Original language name
Associating physiological functions with genomic variability in hibernating bats
Original language description
The challenges of surviving periods of increased physiological stress elicit selective pressures that drive adaptations to overcome hardships. Bats in the Palearctic region survive winter in hibernation. We sampled single nucleotide polymorphisms (SNPs) in hibernating Myotis myotis bats using double-digest restriction site-associated DNA sequencing and we associated the genomic variability with the observed phenotypes reflecting hibernation site preference, body condition and bat health during hibernation. We did not observe genotype associations between the detrended body condition index, representing fat reserves, and functional genes involved in fat metabolism. Bat body surface temperature, reflecting roost selection, or roost warmth relative to the climate at the site did not show any associations with the sampled genotypes. We found SNPs with associations to macroclimatic variables, characterising the hibernaculum, and blood biochemistry, related to health of the bat. The genes in proximity of the associated SNPs were involved in metabolism, immune response and signal transduction, including chaperones, apoptosis and autophagy regulators and immune signalling molecules. The genetic adaptations included adaptation to tissue repair and protection against tissue damage.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10618 - Ecology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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