Long Non-Coding RNAs and Their Potential Roles in the Vector-Host-Pathogen Triad

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60076658%3A12310%2F21%3A43903756" target="_blank" >RIV/60076658:12310/21:43903756 - isvavai.cz</a>
Alternative codes found
RIV/60077344:_____/21:00549064
Result on the web
<a href="https://www.mdpi.com/2075-1729/11/1/56" target="_blank" >https://www.mdpi.com/2075-1729/11/1/56</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.3390/life11010056" target="_blank" >10.3390/life11010056</a>

Result language
angličtina
Original language name
Long Non-Coding RNAs and Their Potential Roles in the Vector-Host-Pathogen Triad
Original language description
Long non-coding (lnc)RNAs have emerged as critical regulators of gene expression and are involved in almost every cellular process. They can bind to other molecules including DNA, proteins, or even other RNA types such messenger RNA or small RNAs. LncRNAs are typically expressed at much lower levels than mRNA, and their expression is often restricted to tissue- or time-specific developmental stages. They are also involved in several inter-species interactions, including vector-host-pathogen interactions, where they can be either vector/host-derived or encoded by pathogens. In these interactions, they function via multiple mechanisms including regulating pathogen growth and replication or via cell-autonomous antimicrobial defense mechanisms. Recent advances suggest that characterizing lncRNAs and their targets in different species may hold the key to understanding the role of this class of non-coding RNA in interspecies crosstalk. In this review, we present a general overview of recent studies related to lncRNA-related regulation of gene expression as well as their possible involvement in regulating vector-host-pathogen interactions.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
S - Specificky vyzkum na vysokych skolach<br>I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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